18229-61-3Relevant academic research and scientific papers
Identification of an indole series of prostaglandin D2 receptor antagonists
Sturino, Claudio F.,Lachance, Nicolas,Boyd, Michael,Berthelette, Carl,Labelle, Marc,Li, Lianhai,Roy, Bruno,Scheigetz, John,Tsou, Nancy,Brideau, Christine,Cauchon, Elizabeth,Carriere, Marie-Claude,Denis, Danielle,Greig, Gillian,Kargman, Stacia,Lamontagne, Sonia,Mathieu, Marie-Claude,Sawyer, Nicole,Slipetz, Deborah,O'Neill, Gary,Wang, Zhaoyin,Zamboni, Robert,Metters, Kathleen M.,Young, Robert N.
, p. 3043 - 3048 (2008/09/21)
A novel indole series of PGD2 receptor (DP receptor) antagonists is presented. Optimization of this series led to the identification of potent and selective DP receptor antagonists. In particular, antagonists 35 and 36 were identified with Ksu
AROMATIC AMIDES
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, (2008/06/13)
This application relates to a compound of formula I (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.
Cyclopentanoindoles, compositions containing such compounds and methods of treatment
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, (2008/06/13)
Substituted cyclopentanoindole derivatives are antagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases.
