182370-56-5

Basic information

• Product Name: Pentanoic acid,5-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, ethyl ester, (R)- (9CI)
• Synonyms: (R)-N-BOC-5-AMINO-3-HYDROXY-PENTANOIC ACID ETHYL ESTER ;(R)-5-tert-Butoxycarbonylamino-3-hydroxy-pentanoic acid ethyl ester
• CAS NO: 182370-56-5
• Molecular Formula: C12H23 N O5
• Molecular Weight: 261.3147
• Mol File: 182370-56-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 393.5°Cat760mmHg
• Flash Point: 191.8°C
• Appearance: /
• Density: 1.087g/cm³
• Vapor Pressure: 8.04E-08mmHg at 25°C
• Refractive Index: 1.463
• PKA: 12?+-.0.46(Predicted)
• CAS DataBase Reference: Pentanoic acid,5-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, ethyl ester, (R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoic acid,5-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, ethyl ester, (R)- (9CI)(182370-56-5)
• EPA Substance Registry System: Pentanoic acid,5-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, ethyl ester, (R)- (9CI)(182370-56-5)

Safety Data

• Hazardous Substances Data: 182370-56-5(Hazardous Substances Data)

Usage

General Description

Pentanoic acid, 5-[[1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, ethyl ester, (R)- (9CI) is a chemical compound with a complex structure. It is an ethyl ester derivative of pentanoic acid, containing a hydroxy group and an amino group. The compound exists in the R-stereoisomer form. The presence of the hydroxy and amino groups makes it potentially useful in pharmaceutical research and drug development, where it may have applications in the synthesis of various pharmaceutical compounds. Its precise properties and potential uses would require further study and evaluation.

InChI:InChI=1/C12H23NO5/c1-5-17-10(15)8-9(14)6-7-13-11(16)18-12(2,3)4/h9,14H,5-8H2,1-4H3,(H,13,16)/t9-/m1/s1

Upstream product

• 3303-84-2 3-(tert-butyloxycarbonylamino)propionic acid 
• 69619-21-2 5-tert-butoxycarbonylamino-3-oxo-pentanoic acid ethyl ester 

Downstream Products

• 69619-20-1 trans-4-aminomethylbut-2-enoic acid 
• 71609-34-2 5-Amino-3-hydroxy-valeriansaeure 

Relevant articles and documents

PROCESS FOR PREPARING C5 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES

The present invention relates to a process for preparing C5 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids from 1,4-diketo starting materials. The invention further relates to intermediates in this process.

N-substituted-7-amino-5-hydroxy-3-oxoheptanoic acid derivatives and method for producing the same

Compounds represented by the following general structural formula (1) and methods for producing the compounds: STR1 R1 represents a group such as benzyloxycarbonyl, R2 represents a lower alkyl group, R3 represents a hydrogen atom or a protecting group, each of M1 and M2 represents a metal atom, and n represents the atomic valence of M1. Intermediates for HMG-CoA reductase inhibitors can be prepared safely and easily from these compounds.

Syntheses and structure-activity studies of analogues and γ-aminobutyric acid (GABA)

The syntheses of (2RS,4RS)- and (2RS,4SR)-2-hydroxy-4-aminopentanoic acid, (3RS,4R)- and (3RS,4S)-3-hydroxy-4-aminopentanoic acid, (RS)-3-hydroxy-5-aminopentanoic acid, trans-(R)- and trans-(S)-4-amino-2-pentenoic acid and trans-5-amino-2-pentenoic acid are described. The compounds were tested as inhibitors of the binding of 3H-GABA to receptor sites on membranes from rat brains and some of the compounds were tested as inhibitors of the >-uptake to GABA into rat brain slices.