1824-02-8Relevant academic research and scientific papers
Gallium (iii)-catalysed bromocyanation of alkynes: Regio- and stereoselective synthesis of β-bromo-α,β-unsaturated nitriles
Murai, Masahito,Hatano, Ryo,Kitabata, Sachie,Ohe, Kouichi
supporting information; experimental part, p. 2375 - 2377 (2011/04/18)
Treatment of arylacetylenes and cyanogen bromide in ClCH2CH 2Cl with a catalytic amount of GaCl3 afforded (Z)-β-bromoacrylonitriles with high regio- and stereoselectivity.
Some Properties of Cyclopropenone Oximes under Beckmann Reaction Conditions
Yoshida, Hiroshi,Yoshida, Keisuke,Totani, Hiroyuki,Ogata, Tsuyoshi,Matsumoto, Kiyoshi
, p. 3579 - 3582 (2007/10/02)
The reaction of diphenylcyclopropenone oxime (1a) with acetyl or tosyl isocyanate, carboxylic anhydrides, or nitrohalobenzenes yielded the cyclopropenone O-substituted oxime derivatives.Treating with thionyl bromide and chloride 1a gave 3-haloacrylonitriles.Whereas 1a as well as other cyclopropenone oximes, were stable under acidic conditions, heating in methanolic sodium hydroxide gave the ring-opened α,α-dimethoxyketones oximes.
Derivatives of the 1,2-diarylethylene- and pharmaceutical compositions thereof
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, (2008/06/13)
The invention relates to derivatives of 1,2-diarylethylene and to a process for their preparation. The compounds have valuable pharmaceutical properties and may be used as medicaments.
