18240-70-5

Basic information

• Product Name: 2,2-DICHLOROHEXANOIC ACID
• Synonyms: 2,2-DICHLOROHEXANOIC ACID;2,2-DICHLOROHEXANOIC ACID 93%;2,2-Dichlorocaproic acid;2,2-Dichlorohexanoic acid,93%;CH3(CH2)4C(Cl)2COOH
• CAS NO: 18240-70-5
• Molecular Formula: C7H12Cl2O2
• Molecular Weight: 199.07
• Mol File: 18240-70-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 66-67 °C
• Flash Point: 106°C
• Appearance: /
• Density: 1.2968 (rough estimate)
• Vapor Pressure: 0.00635mmHg at 25°C
• Refractive Index: 1.4615-1.4635
• CAS DataBase Reference: 2,2-DICHLOROHEXANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DICHLOROHEXANOIC ACID(18240-70-5)
• EPA Substance Registry System: 2,2-DICHLOROHEXANOIC ACID(18240-70-5)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 45-36/37/39-26
• Hazardous Substances Data: 18240-70-5(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow liquid

InChI:InChI=1/C6H10Cl2O2/c1-2-3-4-6(7,8)5(9)10/h2-4H2,1H3,(H,9,10)/p-1

Upstream product

• 628-73-9 hexanenitrile 
• 111-27-3 hexan-1-ol 
• 57024-78-9 2,2-dichlorohexanal 
• 18240-58-9 1,1,2,2-Tetrachlor-1-trichlorphosphoranylidenamino-hexan 
• 66-25-1 hexanal 

Relevant articles and documents

Total synthesis of (+)- and (-)-decursivine and (±)-serotobenine through a cascade witkop photocyclization/elimination/addition sequence: Scope and mechanistic insights

In this article, the total syntheses of antimalarial compound decursivine and its biologically inactive sibling serotobenine are presented. The biomimetic synthesis of (±)-serotobenine was investigated first, but failed. During the subsequent investigatio

2,2-dichloroaldehydes and 2,2-dichlorocarboxylic acids from 2- picoline·HCl catalyzed chlorination of aldehydes

An efficient preparation of 2,2-dichloroaldehydes and 2,2- dichlorocarboxylic acids has been achieved by chlorination of aldehydes using 2-picoline hydrochloride as recoverable catalyst.

α,α-DICHLOROALDEHYDES AND α,α-DICHLOROCARBOXYLIC ACIDS FROM LONG CHAIN 1-ALKANOLS. IMPROVED CHLORINATION IN THE SYSTEM DMF-CHCl3-MgCl2

Production of α,α-dichloroaldehydes by direct chlorination of 1-alkanols with chlorine gas, catalyzed by DMF and DMF*HCl, was extended to long chain compounds (CnH2n+1OH; n = 5, 6, 8, 10, 12, 14, 16, 18).Two problems specific to the longer chains were solved to obtain isolated yields in the range 70-85 percent; a) parasitic radical chlorination was largely controlled by shielding from light; b) alkyl alkanoate side product (8 percent for n = 8 but 25 percent for n = 16 or 18) was decreased to 0-2 percent in the presence of MgCl2*H2O.Homogeneity of the reaction medium was improved with chloroform as a cosolvent.Oxidation of the aldehydes to dichlorocarboxylic acids proceeded smoothly with aqueous KMnO4 up to the tetradecanal.For the longer chains 30 percent hydrogen peroxide-NaHCO3 in acetone (overnight at 48-52 deg C) was the preferred oxidant.