182482-25-3

Basic information

• Product Name: 2,4,6-Trifluorophenylboronic acid
• Synonyms: 2,4,6-TRIFLUOROPHENYLBORONIC ACID;RARECHEM AH PB 0121;2,4,6-Trifluoronenzeneboronic acid;2,4,6-Trifluorophenylboronic;2,4,6-Trifluorophenylboronic Acid (contains varying aMounts of Anhydride);Trifluorobenzeneboronic aci;2,4,6-trifluorophenyl(dihydroxy)borane;2,4,6-TRIFLUOROBENZENEBORONIC ACID
• CAS NO: 182482-25-3
• Molecular Formula: C₆H₄BF₃O₂
• Molecular Weight: 175.9
• EINECS: -0
• Product Categories: blocks;BoronicAcids;FluoroCompounds;Heterocyclic Compounds;Boronic Acid;Aryl;Organoborons;Boronic Acids;Boronic Acids and Derivatives
• Mol File: 182482-25-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 228-235 °C(lit.)
• Boiling Point: 236 °C at 760 mmHg
• Flash Point: 96.5 °C
• Appearance: White to off-white/Crystalline Powder
• Density: 1.44 g/cm³
• Vapor Pressure: 0.00444mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Solubility: soluble in Methanol
• PKA: 8.26±0.58(Predicted)
• BRN: 8549766
• CAS DataBase Reference: 2,4,6-Trifluorophenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Trifluorophenylboronic acid(182482-25-3)
• EPA Substance Registry System: 2,4,6-Trifluorophenylboronic acid(182482-25-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-22
• Safety Statements: 26-36-36/37/39-22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 182482-25-3(Hazardous Substances Data)

Usage

Chemical Properties

Off-white Cryst

Uses

Different sources of media describe the Uses of 182482-25-3 differently. You can refer to the following data:
1. suzuki reaction
2. Reactant involved in:Synthesis of phenylboronic catechol estersSuzuki-Miyaura coupling reactions with aryl chlorides and unstable polyfluorophenylEnantioselective borane reduction of trifluoroacetophenoneTransmetalation

InChI:InChI=1/C6H4BF3O2/c8-3-1-2-4(9)6(10)5(3)7(11)12/h1-2,11-12H

Upstream product

• 2367-76-2 2,4,6-trifluorobromobenzene 
• 121-43-7 Trimethyl borate 
• 372-38-3 1,3,5-trifluorobenzene 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 1156464-26-4 tris(2,4,6-trifluorophenyl)boroxine 
• 767-78-2 1-deutero-2,4,6-trifluorobenzene 
• 1260503-82-9 (S)-tetrahydro-3,3-diphenyl-1-(2,4,6-trifluorophenyl)-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole 
• 1251914-01-8 5-(2,4,6-trifluorophenyl)benzo[1,3]dioxole 
• 1251914-00-7 2-methoxy-6-(2,4,6-trifluorophenyl)pyridine 
• 1334220-48-2 C₂₅H₂₃F₃N₂O₃ 
• 1334220-58-4 C₂₀H₁₁F₃N₂ 
• 1334220-51-7 C₂₇H₂₇F₃N₂O₃ 
• 1334220-61-9 C₂₂H₁₅F₃N₂ 
• 372-38-3 1,3,5-trifluorobenzene 
• 363-72-4 Pentafluorobenzene 
• 14243-64-2 (triphenylphosphine)gold(I) chloride 
• 41860-46-2 2,2’,4,4’,6,6’-hexafluorobiphenyl 
• 2268-17-9 2,4,6-trifluorophenol 

Relevant articles and documents

Synthetic method for 2,4,6-trifluorophenol

The invention relates to the technical field of organic synthesis, in particular to a synthetic method for 2,4,6-trifluorophenol. The synthetic method comprises the following steps of (1) sequentiallyperforming hydrogen removal reaction and reaction with

Polyfluoroorganoboron-oxygen compounds. 1: Polyfluorinated aryl(dihydroxy)boranes and tri(aryl)boroxins

A general preparative procedure for polyfluorinated aryl(dihydroxy)boranes C6H5-nFnB(OH)2 (n = 3 - 5) is described. Polyfluorinated aryl(dihydroxy)boranes are easily dehydrated to the corresponding tri(aryl)boroxins (C6H5-nFnBO)3 by thermal or chemical treatment. The property of the acids C6H5-nFnB(OH)2 to condensate depends on the number and on the position of the fluorine atoms in the aryl group. Examples of both classes of boron compounds were isolated as pure individuals and characterized by multinuclear NMR spectroscopy.