182489-79-8Relevant academic research and scientific papers
Enantioselective Rh-catalyzed hydrogenation of enol acetates and enol carbamates with monodentate phosphoramidites
Panella, Lavinia,Feringa, Ben L.,De Vries, Johannes G.,Minnaard, Adriaan J.
, p. 4177 - 4180 (2007/10/03)
(Chemical Equation Presented) Monodentate phosphoramidites, in particular PipPhos and its octahydro analogue, are excellent ligands for the rhodium-catalyzed asymmetric hydrogenation of aromatic enol acetates, enol carbamates, and 2-dienol carbamates up to 98% ee. These latter substrates were hydrogenated selectively to the carbamates of the allyl alcohol.
α-Zinc O-vinyl carbamates as anionic Friedel-Crafts equivalents. Cross coupling reactions with aryl and heteroaryl halides and triflates
Superchi, Stefano,Sotomayor, Nuria,Miao, Guobin,Joseph, Babu,Snieckus, Victor
, p. 6057 - 6060 (2007/10/03)
A mild, efficient, and general Negishi cross coupling protocol, 4 + 5 → 6 is reported; the hydrolysis of products 6 to acetophenones demonstrates the anionic Friedel-Crafts equivalency of the overall synthetic operation.
