182557-69-3Relevant academic research and scientific papers
Hydroxamic acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase
Patel, Dinesh V.,Young, Marian G.,Robinson, Simon P.,Hunihan, Lisa,Dean, Brenda J.,Gordon, Eric M.
, p. 4197 - 4210 (2007/10/03)
The rational design, synthesis, and activity of novel, hydroxamic acid- based, collective bisubstrate analog inhibitors of farnesyl protein transferase (FPT) is described. This class of compounds differ structurally from the conventional FPT inhibitors by
