182676-02-4Relevant articles and documents
N-Heterocyclic carbene copper-catalyzed direct alkylation of terminal alkynes with non-activated alkyl triflates
Jin, Liqun,Hao, Wangfang,Xu, Jianeng,Sun, Nan,Hu, Baoxiang,Shen, Zhenlu,Mo, Weimin,Hu, Xinquan
supporting information, p. 4124 - 4127 (2017/04/13)
(NHC)-Cu-catalyzed C(sp)-C(sp3) bond formation has been successfully achieved under mild conditions. Nonactivated alkyl triflates, which could be easily derived from alcohols, were utilized as C-O electrophiles. Mechanistic studies suggested th
Oxidative cross-coupling through double transmetallation: Surprisingly high selectivity for palladium-catalyzed cross-coupling of alkylzinc and alkynylstannanes
Zhao, Yingsheng,Wang, Haibo,Hou, Xiaohui,Hu, Yanhe,Lei, Aiwen,Zhang, Heng,Zhu, Lizheng
, p. 15048 - 15049 (2007/10/03)
Two different organometallic reagents now can cross-couple together with the oxidative cross-coupling strategy. Palladium catalyzed oxidative cross-couplings of alkylzinc and alkynylstannane reagents using desyl chloride as the oxidant have been explored, which produce the desired Csp-Csp3 cross-coupling product in surprisingly high selectivity and yields. The current catalytic system tolerates the presence of β-H, and the reactions using long chain alkyl zinc reagents gave the cross-coupling product in excellent yields and selectivities. Copyright
