182821-27-8

Basic information

• Product Name: SLV 306
• Synonyms: SLV 306;Daglutril;2-((S)-3-(1-((R)-2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentanecarboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid
• CAS NO: 182821-27-8
• Molecular Formula: C31H38N2O6
• Molecular Weight: 534.64322
• Mol File: 182821-27-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 802.3°C at 760 mmHg
• Flash Point: 439°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 3.6E-27mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: SLV 306(CAS DataBase Reference)
• NIST Chemistry Reference: SLV 306(182821-27-8)
• EPA Substance Registry System: SLV 306(182821-27-8)

Safety Data

• Hazardous Substances Data: 182821-27-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C31H38N2O6/c1-2-39-29(37)24(15-14-22-10-4-3-5-11-22)20-31(18-8-9-19-31)30(38)32-25-17-16-23-12-6-7-13-26(23)33(28(25)36)21-27(34)35/h3-7,10-13,24-25H,2,8-9,14-21H2,1H3,(H,32,38)(H,34,35)/t24-,25+/m1/s1

Relevant articles and documents

BENZAZEPINE-, BENZOXAZEPINE- AND BENZOTHIAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds with neutral endopeptidase (NEP) inhibitory activity corresponding to the formula I STR1 in which R 1 is a lower alkoxy-lower-alkyl group whose lower alkoxy radical is substituted by a lower alkoxy group, or a phenyl-lower-alkyl or phenyloxy-lower-alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or a naphthyl-lower-alkyl group, A is CH 2, O or S,R 2 is hydrogen or halogen,R. sup.3 is hydrogen or halogen,R 4 is hydrogen or a group forming a biolabile ester, andR 5 is hydrogen or a group forming a biolabile ester, and the physiologically acceptable acid addition salts thereof.