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3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxois a complex chemical compound characterized by a quinoline ring, a cyclopropyl group, an ethoxy group, a fluoro group, and a piperazinyl group. It functions as a potent and selective inhibitor of the bacterial enzyme DNA gyrase, which plays a crucial role in bacterial DNA replication and transcription. 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxois distinguished by its unique structure and mechanism of action, making it a significant asset in combating bacterial infections.

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  • 1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-methyl-piperazin-1-yl)-4-oxo-Quinolin-3-carboxylic acid

    Cas No: 182868-72-0

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  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-

    Cas No: 182868-72-0

  • USD $ 10.0-10.0 / Milligram

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  • 182868-72-0 Structure
  • Basic information

    1. Product Name: 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-
    2. Synonyms: 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-ethoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-;1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-methyl-piperazin-1-yl)-4-oxo-Quinolin-3-carboxylic acid;1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-methylpi...
    3. CAS NO:182868-72-0
    4. Molecular Formula: C20H24FN3O4
    5. Molecular Weight: 389.4206632
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 182868-72-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 613.4°C at 760 mmHg
    3. Flash Point: 324.8°C
    4. Appearance: /
    5. Density: 1.355g/cm3
    6. Vapor Pressure: 6.64E-16mmHg at 25°C
    7. Refractive Index: 1.607
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    9. Solubility: N/A
    10. PKA: 6.43±0.50(Predicted)
    11. CAS DataBase Reference: 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-(CAS DataBase Reference)
    12. NIST Chemistry Reference: 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-(182868-72-0)
    13. EPA Substance Registry System: 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-(182868-72-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 182868-72-0(Hazardous Substances Data)

182868-72-0 Usage

Uses

Used in Pharmaceutical Industry:
3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxois utilized as an antibacterial agent for its effectiveness against a broad spectrum of bacterial infections. It is particularly valuable in treating infections caused by multi-drug resistant strains due to its ability to inhibit the essential DNA gyrase enzyme, thereby disrupting the bacteria's replication and transcription processes.
Used in Research and Development:
In the field of microbiology and pharmaceutical research, 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo- serves as a valuable tool for studying the mechanisms of bacterial resistance and the development of new antibiotics. Its selectivity for DNA gyrase makes it an ideal candidate for investigating the enzyme's role in bacterial survival and resistance to existing treatments.
Used in Clinical Medicine:
3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxois employed in clinical settings to treat patients suffering from bacterial infections that are unresponsive to conventional antibiotics. Its unique mode of action provides a new avenue for treating drug-resistant infections and improving patient outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 182868-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,8,6 and 8 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 182868-72:
(8*1)+(7*8)+(6*2)+(5*8)+(4*6)+(3*8)+(2*7)+(1*2)=180
180 % 10 = 0
So 182868-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H24FN3O4/c1-3-28-19-16-13(8-15(21)17(19)23-7-6-22-11(2)9-23)18(25)14(20(26)27)10-24(16)12-4-5-12/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27)

182868-72-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-cyclopropyl-8-ethoxy-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:182868-72-0 SDS

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