182869-01-8

Basic information

• Product Name: 1-tert-butyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• CAS NO: 182869-01-8
• Molecular Formula: C₁₉H₂₅FN₄O₃
• Molecular Weight: 376.4252
• Mol File: 182869-01-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 551.4°C at 760 mmHg
• Flash Point: 287.3°C
• Density: 1.289g/cm³
• Vapor Pressure: 5.43E-13mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 1-tert-butyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-butyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(182869-01-8)
• EPA Substance Registry System: 1-tert-butyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(182869-01-8)

Safety Data

• Hazardous Substances Data: 182869-01-8(Hazardous Substances Data)

Usage

Chemical class

Fluoroquinolone antibiotics

Derivation

Synthetic derivative of nalidixic acid

Spectrum of activity

Broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria

Target enzymes

Bacterial DNA gyrase and topoisomerase IV

Function

Potent inhibitor of the target enzymes, essential for bacterial DNA replication and repair

Medical application

Treatment of various bacterial infections, including respiratory, urinary tract, and skin infections

Advantage

Strong antibacterial activity and low toxicity to human cells

Limitations

Potential development of bacterial resistance and possible side effects