18289-63-9

Basic information

• Product Name: ethyl 3-methyl-2-nitrobut-2-enoate
• CAS NO: 18289-63-9
• Molecular Formula: C₇H₁₁NO₄
• Molecular Weight: 173.1665
• Mol File: 18289-63-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 257°C at 760 mmHg
• Flash Point: 113.5°C
• Density: 1.127g/cm³
• Vapor Pressure: 0.0149mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: ethyl 3-methyl-2-nitrobut-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-methyl-2-nitrobut-2-enoate(18289-63-9)
• EPA Substance Registry System: ethyl 3-methyl-2-nitrobut-2-enoate(18289-63-9)

Safety Data

• Hazardous Substances Data: 18289-63-9(Hazardous Substances Data)

Upstream product

• 638-10-8 ethyl 3-methylbut-2-enoate 
• 7697-37-2 nitric acid 

Downstream Products

• 494804-47-6 β-benzylsulfanyl-α-nitro-isovaleric acid ethyl ester 
• 100718-35-2 2-benzoylamino-3-methyl-crotonic acid ethyl ester 
• 5398-45-8 N-benzoyl-S-benzyl-DL-penicillamine 
• 159000-75-6 S-benzyl-D,L-penicillamine 
• 59-53-0 NAP 
• 516-06-3 D,L-valine 
• 22078-04-2 α,β-dehydrovaline ethylester 

Relevant articles and documents

Exploration of the molecular origin of the azinomycin epoxide: Timing of the biosynthesis revealed

(Equation Presented) Streptomyces sahachiroi whole cell feeding experiments, utilizing putative precursors labeled with stable isotopes, established that the epoxide unit of the DNA cross-linked agents, azinomycin A and B, proceeds via a valine-dependent pathway and that hydroxylation and dehydration precedes formation of the terminal epoxide. Sodium 3-methyl-2-oxobutenoate, formed through a transimination reaction, was shown to be the penultimate precursor incorporated into the azinomycin epoxide.