182912-78-3Relevant articles and documents
Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein
Akagi, Ken-ichi,Masuda, Yuichi,Monobe, Yoko,Shibata, Kana,Tanaka, Fumiya
, (2020)
Aggregation of 42-residue amyloid β-protein (Aβ42) can be prevented by β-sheet breaker peptides (BSBps) homologous to LVFFA residues, which are included in a β-sheet region of Aβ42 aggregates. To enhance the affinity of BSBps to the Aβ42 aggregates, we de