182920-45-2

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 192935-78-7 3-phenyl-1-(2-(p-tolylethynyl)phenyl)prop-2-yn-1-ol 
• 624-31-7 4-tolyl iodide 
• 38846-64-9 2-ethynylbenzaldehyde 
• 189008-33-1 2-[2-(4-methylphenyl)ethynyl]benzaldehyde 

Relevant academic research and scientific papers

A surprising switch from the Myers-Saito cyclization to a novel biradical cyclization in enyne-allenes: Formal diels-alder and ene reactions with high synthetic potential

If there is an aryl substituent on the acetylene terminus of enyne allenes, then its reaction mode may be changed from the Myers-Saito cyclization to a novel C2-C6 cyclization resulting in a net intramolecular Diels-Alder or ene reaction. As a consequence, the thermal cyclization of readily accessible acyclic enyne allenes can be utilized for the synthesis of complex benzofulvene and benzofluorene derivatives. Kinetic results of the C2-C6 cyclization reaction indicate a two-step reaction pathway with a benzofulvene biradical intermediate.

Intramolecular formal Diels-Alder reaction in enyne allenes. A new synthetic route to benzofluorenes and indeno[1,2-g]quinolines

Through the use of aryl substituents at the acetylene terminus in enyne allenes the reaction mode may be changed from the Myers-Saito cyclization to a C2-C6 cyclization resulting in a net intramolecular Diels-Alder reaction. As a con