183006-45-3

Basic information

• Product Name: 6-{N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-hydrazino}-1-methyl-1H-pyrimidine-2,4-dione
• Synonyms: 6-{N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-hydrazino}-1-methyl-1H-pyrimidine-2,4-dione
• CAS NO: 183006-45-3
• Molecular Weight: 278.698
• Mol File: 183006-45-3.mol

Chemical Properties

• CAS DataBase Reference: 6-{N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-hydrazino}-1-methyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-hydrazino}-1-methyl-1H-pyrimidine-2,4-dione(183006-45-3)
• EPA Substance Registry System: 6-{N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-hydrazino}-1-methyl-1H-pyrimidine-2,4-dione(183006-45-3)

Safety Data

• Hazardous Substances Data: 183006-45-3(Hazardous Substances Data)

Upstream product

• 31737-09-4 6-chloro-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Fervenulin, 4-Deazafervenulin and 5-Deazaalloxazine Analogues. Synthesis and Antimicrobial Activity

6-Chloro-1-methyluracil 1 was converted to 6-hydrazino- 2, and/or 6-arylamino-1-methyluracils 3a-d.Condensation of 2 with aldehydes led to the corresponding 6-hydrazones 4a-c.Cyclization of 2 with benzil provided 4-deaza-6-demethyl fervenulin 6.Refluxing 4a-c with NaNO2/AcOH afforded 4-deazafervenulins analogues 7a-c, the nitrosation of compound 2 provided 6-azido-1-methyluracil 8.The formylation of 3a-d by Vilsmeier reagent afforded 5-deazaalloxazines 10a-d.Reaction of 1 with cyanoacetic acid hydrazide led to the formation of 11. - Keywords: 6-chloro-1-methyluracil; 6-demethyl fervenulin; 5-deazaalloxazin