183107-05-3

Upstream product

• 186587-70-2 Toluene-4-sulfonic acid 3-benzyloxy-2-(diisopropoxy-phosphorylmethoxy)-propyl ester 
• 66224-66-6 adenine 
• 1517-05-1 2-azidoethanol 
• 183107-01-9 [2-(6-Amino-purin-9-yl)-1-benzyloxymethyl-ethoxymethyl]-phosphonic acid 
• 32315-10-9 bis(trichloromethyl) carbonate 

Relevant academic research and scientific papers

"Abbreviated" NAD+analogues containing a phosphonate function

"Abbreviated" NAD+ analogues with anionic phosphonate function as a part of the link between the adenine and nicotinamide moieties, 9-(2-phosphonomethoxyethyl)adenine 2-(3-carbamoylpyridinium)ethyl ester (1a), (R)- and (S)-9-(2-phosphonomethoxypropyl)adenine 2-(3-carbamoylpyridinium)ethyl ester (1b and 1c), (RS)-9-(3-hydroxy-2-phosphonomethoxypropyl)adenine 2-(3-carbamoylpyridinium)ethyl ester (1d), and (S)- and (R)-1-[3-(adenin-9-yl)-2-phosphonatomethoxypropyl]-3-carbamoylpyridinium (2a and 2b), were prepared by multistep syntheses using the Zincke reaction in the last step.

"Abbreviated" NAD+ Analogues Containing a Phosphonate Function

New types of "abbreviated" NAD+ analogues with anionic phosphonate function as a part of the link between the adenine and nicotinamide moieties were prepared by multistep syntheses using the Zincke reaction as the last step.The structures of the compounds were derived from the biologically active acyclic nucleotide analogues.