1832-98-0Relevant academic research and scientific papers
Isolation and characterization of a new allelochemical from seeds of Adenanthera pavonina linn
Yadava,Vishwakarma, Umesh Kumar
, p. 4902 - 4904 (2013/07/28)
A new allelochemical (1), m.p. 282-284 °C, m.f. C31H 36O19, [M]+ 712 (FABMS), has been isolated from methanolic extract of the seeds of Adenanthera pavonina Linn. alongwith two known compounds 2',4',7-trihydroxy isoflavone and isovitexin. The structure of a new compound was characterized as 3,5,7,3',4'-pentahydroxy flavone-3'-O-α-L- rhamnopyranosyl-(1→4)-O-α-L-arabinopyranosyl-(1→3)- O-b-D- xylopyranoside, by various colour reactions, spectral analysis and chemical degradations.
Structure-activity requirements for flavone cytotoxicity and binding to tubulin
Beutler, John A.,Hamel, Ernest,Vlietinck, Arnold J.,Haemers, Achiel,Rajan, Padinchare,Roitman, James N.,Cardellina II, John H.,Boyd, Michael R.
, p. 2333 - 2338 (2007/10/03)
A series of 79 flavones related to centaureidin (3,6,4'-trimethoxy- 5,7,3'-trihydroxyflavone, 1) was screened for cytotoxicity in the NCI in vitro 60-cell line human tumor screen. The resulting cytotoxicity profiles of these flavones were compared for deg
ANTIMICROBIAL FLAVONOIDS FROM PSIADIA TRINERVIA AND THEIR METHYLATED AND ACETYLATED DERIVATIVES
Wang, Ying,Hamburger, Matthias,Gueho, Joseph,Hostettmann, Kurt
, p. 2323 - 2328 (2007/10/02)
Key Word Index - Psiadia trinervia; Compositae; flavonoids; antifungal; antibacterial; Cladosporium cucumerinum; Bacillus cereus; bioautography.Abstract - From a dichloromethane extract and a hydrolysed methanolic extract from the leaves of Psiadia trinervia, 13 3-methylated flavonol have beeen isolated.Their structures were established by the usual spectoscopic methods (UV, EIMS, 1H and 13CNMR).Ayanin, casticin, chrysosplenol-D and 5,7,4'-trihydroxy-3,8-dimethoxyflavone were responsible for the antifungal activity found in the preliminary screening.Chrysosplenol-D, isokaemferide, 5,7,4'-trihydroxy-3,3'-dimethoxyflavone and 5,7,4'-trihydroxy-3,8-dimethoxyflavone displayed antibacterial activity.Twenty-nine derivatives were prepared by permethylation and selective methylation of the free hydroxyl group at C-5.The antimicrobial activities of the isolates and derivatives were determined by bioautographic assays using C. cucumerinum and B. cereus as test organisms.
