18321-16-9

Basic information

• Product Name: 1,2-Dithiolane, 1,1-dioxide
• Synonyms: 1,2-dithiolane-1,1-dioxide;Propanthiosulton;1,3-Dithiolan-1,1-dioxid
• CAS NO: 18321-16-9
• Molecular Formula: C3H6O2S2
• Molecular Weight: 138.211
• Mol File: 18321-16-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 334.4±9.0 °C(Predicted)
• Density: 1.458±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,2-Dithiolane, 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dithiolane, 1,1-dioxide(18321-16-9)
• EPA Substance Registry System: 1,2-Dithiolane, 1,1-dioxide(18321-16-9)

Safety Data

• Hazardous Substances Data: 18321-16-9(Hazardous Substances Data)

Usage

Physical State

Colorless liquid

Uses

a. Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds
b. Reagent in organic chemistry reactions, particularly in the formation of carbon-carbon bonds

Properties

a. Potent antioxidant
b. Potential therapeutic properties in the treatment of various diseases, including cancer and inflammatory conditions

Safety Precautions

Handle with care as it can be hazardous if not handled properly.

Upstream product

• 505-23-7 1,3 dithiane 
• 6572-95-8 1,5-dithiocane 
• 6007-26-7 2-methyl-1,3-dithian 

Downstream Products

• 111848-89-6 Sodium; 3-phenyldisulfanyl-propane-1-sulfinate 
• 111848-87-4 Sodium; 3-p-tolyldisulfanyl-propane-1-sulfinate 

Relevant articles and documents

Photooxidation of 1,5-dithiacyclooctane. A novel C-S bond cleavage

Sensitized photooxidation of 1,5-dithiacyclooctane (1,5-DTCO) has been investigated in various solvents. At high conversions, a novel C-S bond cleavage occurs. Significant solvent effects are also observed. At high concentration (0.05-0.1 M) in methanol, more than 90% of the corresponding monosulfoxide and a mixture of cis- and trans-bissulfoxides are produced. In aprotic solvents (benzene, chloroform, acetone, and acetonitrile), novel cleavage products (1,2-dithiolane 1-oxide, 1,2-dithiolane 1,1-dioxide, and acrolein) were obtained in addition to the monosulfoxide and bissulfoxides. The cleavage products derive mostly from reaction of the primary monosulfoxide (1,5-DTCO 1-oxide) with singlet oxygen. Unstable compounds oxidized α to the sulfur atom were detected by NMR spectroscopy and shown to be intermediate in the formation of the cleavage products.