18325-78-5

Basic information

• Product Name: 1-(1-Hydroxy-ethyl)-4,4-dimethyl-cyclohexen
• Synonyms: 1-(1-Hydroxy-ethyl)-4,4-dimethyl-cyclohexen
• CAS NO: 18325-78-5
• Molecular Weight: 154.252
• Mol File: 18325-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1-Hydroxy-ethyl)-4,4-dimethyl-cyclohexen(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Hydroxy-ethyl)-4,4-dimethyl-cyclohexen(18325-78-5)
• EPA Substance Registry System: 1-(1-Hydroxy-ethyl)-4,4-dimethyl-cyclohexen(18325-78-5)

Safety Data

• Hazardous Substances Data: 18325-78-5(Hazardous Substances Data)

Upstream product

• 5773-37-5 4,4-dimethyl-1-cyclohexene acetate 

Downstream Products

• 1072430-67-1 C₁₀H₁₈O 
• 1072430-68-2 C₁₂H₂₀O₂ 
• 1072430-63-7 C₁₃H₂₂O₂ 
• 1072430-70-6 C₁₄H₂₄O₂ 
• 1072430-69-3 C₁₄H₂₄O₂ 

Relevant articles and documents

Cyclization of N,N-diethylgeranylamine N-oxide in one-pot operation: preparation of cyclic terpenoid-aroma chemicals

Acid promoted cyclization of the geranylamine N-oxide (E)-4 followed by base-catalyzed intramolecular aldol condensation afforded 1-acetyl-4,4-dimethyl-1-cyclohexene (7) in one-pot operation. Reduction of 7, which possess strong fruity odor, followed by lipase-catalyzed kinetic resolution furnished the acetate (R)-26 (>49.9% yield, >99% ee) and the recovered alcohol (S)-25 (>49.9% yield, >99% ee, herbal odor).