183272-51-7

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 183505-22-8 (-)-(1R,2R,3S,4R)-4-(N-tert-butyloxycarbonyl)amino-2,3-dimethylmethylenedioxy-1-(hydroxymethyl)cyclopentane 
• 79200-56-9 (-)-2-azabicyclo[2.2.1]hept-5-en-3-one 
• 178032-63-8 [3aS-(3aα,4β,7β,7aα)]tetrahydro-2,2-dimethyl-4,7-methano-1,3-dioxolo[4,5-c]pyridin-6(3aH)-one 
• 79200-55-8 (1R,4S,5R,6S)-5,6-dihydroxy-2-azabicyclo[2.2.1]heptan-3-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 183272-49-3 tert-butyl (3aS,4R,7S,7aR)-2,2-dimethyl-6-oxotetrahydro-4,7-methano[1,3]dioxolo[4,5-c]pyridine-5(4H)-carboxylate 

Relevant academic research and scientific papers

Synthesis of carbocyclic NAD+ containing a methylenebisphosphonate linkage for the investigation of ADP-ribosyl cyclase

A stereospecific synthesis of carbocyclic NAD+ incorporating a methylenebisphosphonatelinkage in place of the natural pyrophosphate gives an analogue 4 of the natural coenzyme NAD+ 3a designed to act as an inhibitor of ADP-ribosyl cy

The Synthesis of a Bisphosphonate Carbocyclic NAD+ Analogue for the Investigation of ADP-Ribosyl Cyclase

A novel stereospecific synthesis of carbocyclic NAD+ has been developed which allows incorporation of a bisphosphonate linkage in place of the natural pyrophosphate.This analogue has increased stability to enzymatic degradation and has potential as an inh