183275-87-8

Basic information

• Product Name: BENZYL-(TETRAHYDRO-FURAN-2-YLMETHYL)-AMINE
• Synonyms: SPECS AG-390/25100008;TIMTEC-BB SBB007201;CHEMBRDG-BB 6605871;BENZYL-(TETRAHYDRO-FURAN-2-YLMETHYL)-AMINE;ART-CHEM-BB B023159;AKOS B023159;1-phenyl-N-(tetrahydrofuran-2-ylmethyl)methanamine(SALTDATA: HCl);1-phenyl-N-(tetrahydrofuran-2-ylmethyl)methanamine 1HCl
• CAS NO: 183275-87-8
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.27
• Mol File: 183275-87-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 294.1 °C at 760 mmHg
• Flash Point: 118.8 °C
• Appearance: /
• Density: 1.023 g/cm³
• Vapor Pressure: 0.00166mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: BENZYL-(TETRAHYDRO-FURAN-2-YLMETHYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL-(TETRAHYDRO-FURAN-2-YLMETHYL)-AMINE(183275-87-8)
• EPA Substance Registry System: BENZYL-(TETRAHYDRO-FURAN-2-YLMETHYL)-AMINE(183275-87-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 183275-87-8(Hazardous Substances Data)

Usage

General Description

Benzyl-(tetrahydro-furan-2-ylmethyl)-amine is a chemical compound that belongs to the class of organic compounds known as benzylic amines. These are organonitrogen compounds containing an amine group attached to a benzyl group. This specific chemical features a tetrahydrofuran ring, which is a five-membered cyclic ether with four carbon atoms and an oxygen atom. BENZYL-(TETRAHYDRO-FURAN-2-YLMETHYL)-AMINE is therefore considered a heterocyclic compound, denoting that it contains atoms of at least two different elements in its rings. It's commonly used in chemical and biomedical research but detailed information related to its potential uses or toxicity levels could not be found. It might be due to it being a specific and niche chemical compound.

InChI:InChI=1/C12H17NO/c1-2-5-11(6-3-1)9-13-10-12-7-4-8-14-12/h1-3,5-6,12-13H,4,7-10H2

Upstream product

• 3003-84-7 Tetrahydrofurfuryl chloride 
• 100-46-9 benzylamine 
• 98-01-1 furfural 
• 4795-29-3 TETRAHYDROFURFURYLAMINE 
• 100-52-7 benzaldehyde 
• 97-99-4 Tetrahydrofurfuryl alcohol 

Relevant articles and documents

Conversion of furfural to tetrahydrofuran-derived secondary amines under mild conditions

The production of amino-containing compounds from biomass is an important goal of research programs. Starting from carbohydrate-based furfural, a simple and highly efficient system was developed for producing a library of secondary and tertiary tetrahydrofurfurylamines under mild conditions (25 °C/1 bar H2) with excellent yields (>90%). Commercially available Pd/Al2O3 proved to be a suitable catalyst and exhibited outstanding performance.

Ruthenium-catalyzed N-alkylation of amines with alcohols under mild conditions using the borrowing hydrogen methodology

Using a simple amino amide ligand, ruthenium-catalyzed one-pot alkylation of primary and secondary amines with simple alcohols was carried out under a wide range of conditions. Using the alcohol as solvent, alkylation was achieved under mild conditions, even as low as room temperature. Reactions occurred with high conversion and selectivity in many cases. Reactions can also be carried out at high temperatures in organic solvent with high selectivity using stoichiometric amounts of the alcohol.