183281-26-7

Basic information

• Product Name: 4⁽⁵⁾-(2-ethyl-2,3-dihydro-2-silainden-2-yl)-1-triphenylmethylimidazole
• CAS NO: 183281-26-7
• Molecular Weight: 470.689
• Mol File: 183281-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4⁽⁵⁾-(2-ethyl-2,3-dihydro-2-silainden-2-yl)-1-triphenylmethylimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4⁽⁵⁾-(2-ethyl-2,3-dihydro-2-silainden-2-yl)-1-triphenylmethylimidazole(183281-26-7)
• EPA Substance Registry System: 4⁽⁵⁾-(2-ethyl-2,3-dihydro-2-silainden-2-yl)-1-triphenylmethylimidazole(183281-26-7)

Safety Data

• Hazardous Substances Data: 183281-26-7(Hazardous Substances Data)

Upstream product

• 20151-87-5 2,2-dichloro-2,3-dihydro-1H-benzo[c]silole 
• 96797-15-8 N-trityl-4⁽⁵⁾-iodoimidazole 
• 20152-09-4 2,2-dimethoxy-2,3-dihydro-1H-benzo[c]silole 
• 925-90-6 ethylmagnesium bromide 

Relevant articles and documents

Synthesis and pharmacological properties of 4(5)-(2-ethyl-2,3-dihydro-2-silainden-2-yl)imidazole, a silicon analogue of atipamezole

4(5)-(2-Ethyl-2,3-dihydro-2-silainden-2-yl)imidazole 2a, 4(5)-(2-methyl-2,3-dihydro-2-silainden-2-yl)imidazole 2b and 4(5)-(2-ethyl-2,3-dihydro-2-silainden-2-yl)-2-methylimidazole 2c, C2 silicon analogues of the commercially available α2-adrenergic receptor antagonist atipamezole 1, were prepared and their pharmacological properties were evaluated. The results show that 2a retained significant affinity for the receptors, and the in vivo pharmacokinetic properties of 2a were comparable to those of 1.