183298-79-5

Upstream product

• 183298-76-2 (4S,5S)-4-benzoyloxymethyl-3-methoxymethyl-5-((1R)-1-methoxymethyloxy-2-propen-1-yl)-2-oxazolidinone 
• 183298-77-3 (4S,5S)-4-hydroxymethyl-3-methoxymethyl-5-((1R)-1-methoxymethyloxy-2-propen-1-yl)-2-oxazolidinone 
• 174582-83-3 (4S,5S)-4-benzyloxymethyl-5-<(1R)-1-hydroxy-2-propen-1-yl>oxazolidin-2-one 
• 174582-88-8 (4S,5S)-3,4-bis(methoxymethyl)-5-<(1R)-1-methoxymethyloxy-2-propen-1-yl>-2-oxazolidinone 
• 93-97-0 benzoic acid anhydride 
• 183298-78-4 (2S,3S,4R)-2-dimethylamino-1-methoxy-4-methoxymethyloxy-5-hexen-3-ol 

Relevant academic research and scientific papers

Syntheses of optically active, unusual, and biologically important hydroxy-amino acids from d-glucosamine

Manipulation of D-glucosamine as a chiral pool including stereoinversion of the C3-hydroxyl group, degradation of the C6-carbon, and/or one carbon homologation at the C1-position realized chiral syntheses of (2S,3S)-dihydroxy-(4S)-amino acid moieties, important structural components of a gastroprotective substance AI-77-B and a group of antitumor substances calyculins.

Chiral syntheses of dihydroxyamino acid moieties of AI-77-B and calyculins from D-glucosamine

Manipulation of cis (4S,5S)-4,5-disubstituted 2-oxazolidinones (4, 5), derived easily from D-glucosamine (1) as a chiral pool, including degradation of the C6-carbon and/or one-carbon homologation at the C1-position allowed chiral syntheses of (2S,3S)-dihydroxy-(4S)-amino acid moieties (6-8), which are important structural components of a gastroprotective substance, AI-77- B, and a group of antitumor substances, calyculins.