183312-07-4

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 183312-23-4 1-[2-(3,3-Dimethyl-but-1-ynyl)-phenyl]-hept-2-yn-1-ol 
• 32359-01-6 hexenylmagnesium bromide 
• 917-92-0 3,3-Dimethylbut-1-yne 
• 183312-34-7 2-(3,3-dimethylbut-1-yn-1-yl)benzaldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 

Relevant academic research and scientific papers

Steric effects in enyne-allene thermolyses: Switch from the Myers-Saito reaction to the C2-C6-cyclization and DNA strand cleavage

The thermal reaction of enyne-allenes 1 with large substituents (tert.-butyl, trimethylsilyl) at the acetylene terminus leads to C2-C6 cyclization products presumably via an intermediate benzofulvene biradical, whereas with a hydrogen substituent the expected Myers-Saito cycloaromatization product is formed. Effective DNA strand scission can be observed when no intramolecular pathway is available.