183313-30-6

Basic information

• Product Name: N1-Benzyl-4-chloro-N2-methyl-N2-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]-N1-[3-(4-pyridyl)-1-[2-(4-pyridyl)ethyl]propyl]-L-phenylalaninamide dimethanesulfonate
• Synonyms: Timcodar dimesilate; VX-853; N-benzyl-3-(4-chlorophenyl)-N-[3-(4-pyridyl)-1-[2-(4-pyridyl)ethyl]propyl]propanamide; methanesulfonic acid; [methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]amino]methanesulfonic acid
• CAS NO: 183313-30-6
• Molecular Formula: C₄₅H₅₃ClN₄O₁₂S₂
• Molecular Weight: 941.5049
• Mol File: 183313-30-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 681.3°C at 760 mmHg
• Flash Point: 365.9°C
• Vapor Pressure: 2.03E-18mmHg at 25°C
• CAS DataBase Reference: N1-Benzyl-4-chloro-N2-methyl-N2-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]-N1-[3-(4-pyridyl)-1-[2-(4-pyridyl)ethyl]propyl]-L-phenylalaninamide dimethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: N1-Benzyl-4-chloro-N2-methyl-N2-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]-N1-[3-(4-pyridyl)-1-[2-(4-pyridyl)ethyl]propyl]-L-phenylalaninamide dimethanesulfonate(183313-30-6)
• EPA Substance Registry System: N1-Benzyl-4-chloro-N2-methyl-N2-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]-N1-[3-(4-pyridyl)-1-[2-(4-pyridyl)ethyl]propyl]-L-phenylalaninamide dimethanesulfonate(183313-30-6)

Safety Data

• Hazardous Substances Data: 183313-30-6(Hazardous Substances Data)

Usage

General Description

N1-Benzyl-4-chloro-N2-methyl-N2-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]-N1-[3-(4-pyridyl)-1-[2-(4-pyridyl)ethyl]propyl]-L-phenylalaninamide dimethanesulfonate, also known as CCR9 antagonist, is a complex chemical compound with potential therapeutic applications. It is a dimethanesulfonate salt and an orally bioavailable small molecule that selectively and competitively binds to and blocks the activity of the chemokine receptor CCR9, which is involved in the migration and homing of certain immune cells. This chemical is of interest due to its potential use in the treatment of inflammatory and autoimmune diseases, as well as solid tumors. Its precise mechanism of action and therapeutic potential are still under investigation, but it shows promise as a targeted therapy for a range of conditions.