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Desmethyl Erlotinib Acetate, also known as Desmethyl Erlotinib (E625000) derivative, is a pale brown solid with significant chemical properties. It is a derivative of Erlotinib, a potent and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, which plays a crucial role in the treatment of various types of cancer.

183320-15-2

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183320-15-2 Usage

Uses

Used in Pharmaceutical Industry:
Desmethyl Erlotinib Acetate is used as an active pharmaceutical ingredient for the development of targeted cancer therapies. It is particularly effective against non-small cell lung cancer (NSCLC) and pancreatic cancer, which often exhibit EGFR mutations. The compound works by inhibiting the EGFR tyrosine kinase activity, thereby blocking the signaling pathways that promote cancer cell growth and proliferation.
Used in Research and Development:
In the field of research and development, Desmethyl Erlotinib Acetate serves as a valuable compound for studying the mechanisms of EGFR inhibition and its potential applications in cancer treatment. It can be used to investigate the structure-activity relationship of EGFR inhibitors and to develop novel, more potent, and selective inhibitors for cancer therapy.
Used in Drug Synthesis:
Desmethyl Erlotinib Acetate is also utilized as a key intermediate in the synthesis of other EGFR inhibitors and related compounds. Its chemical properties make it a suitable candidate for further modification and optimization to improve the efficacy, selectivity, and pharmacokinetic properties of EGFR-targeted drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 183320-15-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,3,2 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 183320-15:
(8*1)+(7*8)+(6*3)+(5*3)+(4*2)+(3*0)+(2*1)+(1*5)=112
112 % 10 = 2
So 183320-15-2 is a valid CAS Registry Number.

183320-15-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethyl acetate

1.2 Other means of identification

Product number -
Other names Desmethyl Erlotinib Acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:183320-15-2 SDS

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