183321-82-6

Basic information

• Product Name: Erlotinib iMpurity
• Synonyms: Erlotinib iMpurity;Erlotinib iMpurity, 6,7-bis(2-chloroethoxy)
• CAS NO: 183321-82-6
• Molecular Formula: C20H17Cl2N3O2
• Molecular Weight: 402.27388
• EINECS: -0
• Mol File: 183321-82-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Erlotinib iMpurity(CAS DataBase Reference)
• NIST Chemistry Reference: Erlotinib iMpurity(183321-82-6)
• EPA Substance Registry System: Erlotinib iMpurity(183321-82-6)

Safety Data

• Hazardous Substances Data: 183321-82-6(Hazardous Substances Data)

Usage

Description

Erlotinib iMpurity, also known as 6,7-Bis(2-chloroethoxy)-N-(3-ethynylphenyl)-4-quinazolinamine, is an intermediate compound used in the preparation of (bis(morpholinoalkoxy))(phenylamino)quinazolines derivatives. These derivatives act as epidermal growth factor receptor (EGFR) inhibitors, which possess anti-proliferative activity against tumor cells. Erlotinib iMpurity plays a crucial role in the development of targeted therapies for cancer treatment.

Uses

Used in Pharmaceutical Industry:
Erlotinib iMpurity is used as an intermediate compound for the synthesis of EGFR inhibitors. These inhibitors are essential in the development of anti-proliferative drugs that target tumor cells, particularly those overexpressing the EGFR.
Used in Cancer Treatment:
Erlotinib iMpurity contributes to the creation of drugs that have anti-proliferative activity against various types of cancer cells. By targeting the EGFR, these drugs can potentially halt the growth and spread of cancer, providing a more targeted and effective treatment option for patients.
Used in Research and Development:
Erlotinib iMpurity is also utilized in research and development for the study of EGFR inhibitors and their potential applications in cancer therapy. This includes understanding the mechanisms of action, optimizing drug delivery, and evaluating the safety and efficacy of these compounds in preclinical and clinical studies.