183376-76-3Relevant articles and documents
Thermal removal of BOC-protecting groups during preparation of open-chain polyamines
Krakowiak, Krzysztof E.,Bradshaw, Jerald S.
, p. 3999 - 4004 (2007/10/03)
Per-N-tosylated 3,8-diaza-1,10-decanediamine (9), 4,9-diaza-1,12-dodecanediamine (spermine) (10) and 3,6,9,14,17,20-hexaaza-1,22-docosanediamine (11) were prepared by treating mono-BOC-protected, per-N-tosylated 1,2-ethanediamine (5), 1,3-propanediamine (6) and triethylenetetraamine (7), respectively, with 1,4-dibromobutane and removing the BOC-protecting groups at 100-120°C.