183428-17-3

Basic information

• Product Name: Thymidine, 3',5'-dideoxy-3,5'-bis[(2-nitrophenyl)dithio]-
• CAS NO: 183428-17-3
• Molecular Formula: C22H20N4O7S4
• Molecular Weight: 580.687
• Mol File: 183428-17-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Thymidine, 3',5'-dideoxy-3,5'-bis[(2-nitrophenyl)dithio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 3',5'-dideoxy-3,5'-bis[(2-nitrophenyl)dithio]-(183428-17-3)
• EPA Substance Registry System: Thymidine, 3',5'-dideoxy-3,5'-bis[(2-nitrophenyl)dithio]-(183428-17-3)

Safety Data

• Hazardous Substances Data: 183428-17-3(Hazardous Substances Data)

Upstream product

• 7669-54-7 2-nitrobenzenesulfenyl chloride 
• 183428-15-1 1-[(2R,4S,5R)-4-(4-Methoxy-benzylsulfanyl)-5-(4-methoxy-benzylsulfanylmethyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 

Downstream Products

• 491837-17-3 S,S'-bis(2-nitrophenylsulfanyl)-3',5'-dithio-2'-deoxy-β-4-N-n-octanoyladenosine 
• 491837-18-4 S,S'-bis(2-nitrophenylsulfanyl)-3',5'-dithio-2'-deoxy-α-4-N-n-octanoyladenosine 

Relevant articles and documents

Artificial nucleosides possessing metal binding sites at the 3′- and 5′-positions of the deoxyribose moieties

This paper describes a convenient synthetic procedure for nucleoside mimics, 1-6, in which the 3′,5′-hydroxy groups of natural 2′-deoxythymidine or 2′-deoxyadenosine are replaced by thiol, amine, or alkylthiol groups. Such nucleosides would be built up into a single DNA strand with cooperative participation of metal coordination, where internucleoside linkages are replaced by metal complexation motifs. The X-ray crystal structure and complexation behaviors of 3′,5′-dithiothymidine, 1, with AuI are also reported.