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2-Bromo-6-fluoro-4-methylaniline, a chemical compound with the molecular formula C7H7BrFN, is a derivative of aniline. It is characterized by the presence of a bromine atom at the 2-position, a fluorine atom at the 6-position, and a methyl group at the 4-position. 2-BROMO-6-FLUORO-4-METHYLANILINE is known for its versatile applications in various industries.

18349-09-2

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18349-09-2 Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-6-fluoro-4-methylaniline is used as an intermediate in the synthesis of pharmaceuticals for its potential anti-inflammatory and antibacterial properties. It plays a crucial role in the development of medicinal compounds that can address various health conditions.
Used in Agrochemical Industry:
2-BROMO-6-FLUORO-4-METHYLANILINE is also utilized in the production of agrochemicals, contributing to the development of effective solutions for agricultural applications, such as pesticides and herbicides, to protect crops and enhance yield.
Used in Dye and Pigment Industry:
2-Bromo-6-fluoro-4-methylaniline is employed in the manufacturing of dyes and pigments due to its chemical properties. It serves as a valuable intermediate in creating a wide range of colorants used in various industries, including textiles, plastics, and printing inks.
Used in Specialty Chemicals Production:
Furthermore, 2-BROMO-6-FLUORO-4-METHYLANILINE finds application in the production of specialty chemicals, which are used in specific industries for their unique properties. These specialty chemicals can be found in applications such as coatings, adhesives, and sealants, where their distinct characteristics are highly beneficial.

Check Digit Verification of cas no

The CAS Registry Mumber 18349-09-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,4 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18349-09:
(7*1)+(6*8)+(5*3)+(4*4)+(3*9)+(2*0)+(1*9)=122
122 % 10 = 2
So 18349-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BrFN/c1-4-2-5(8)7(10)6(9)3-4/h2-3H,10H2,1H3

18349-09-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-BROMO-6-FLUORO-4-METHYLANILINE

1.2 Other means of identification

Product number -
Other names Benzenamine,2-bromo-6-fluoro-4-methyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18349-09-2 SDS

18349-09-2Upstream product

18349-09-2Relevant articles and documents

POLYCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND OR THE COMPOSITION

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Page/Page column 274, (2020/11/03)

Specific polycyclic compounds, a material for an organic electroluminescence device comprising said specific polycyclic compound, an organic electroluminescence device comprising said specific polycyclic compound, an electronic equipment comprising said organic electroluminescence device, a process for preparing said polycyclic compounds, and the use of said polycyclic compounds in an organic electroluminescence. (Formula I) (I)

Direct Formic Acid Mediated Z-Selective Reductive Coupling of Dienes and Aldehydes

Cooze, Christopher,Dada, Raphael,Lundgren, Rylan J.

supporting information, p. 12246 - 12251 (2019/08/01)

Methods for the addition of unsaturated nucleophiles to carbonyls to generate Z-olefin products remain rare and often require either alkyl borane or zinc reductants, limiting their utility. Demonstrated here is that formic acid mediates the Rh-catalyzed,

NOVEL ANTIBIOTICS AND METHODS OF USING SAME

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Page/Page column 72, (2018/05/16)

The present invention includes novel 3,6-diazabicyclo[3.1.1]heptane antibiotic compounds and any salts or solvates thereof. The present invention further includes methods of preparing such compounds, and methods of treating bacterial infection in a subjec

CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF

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Page/Page column 123; 124, (2017/03/21)

Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)

Gopalsamy, Ariamala,Narayanan, Arjun,Liu, Shenping,Parikh, Mihir D.,Kyne, Robert E.,Fadeyi, Olugbeminiyi,Tones, Michael A.,Cherry, Jonathan J.,Nabhan, Joseph F.,LaRosa, Gregory,Petersen, Donna N.,Menard, Carol,Foley, Timothy L.,Noell, Stephen,Ren, Yong,Loria, Paula M.,Maglich-Goodwin, Jodi,Rong, Haojing,Jones, Lyn H.

, p. 3094 - 3108 (2017/04/21)

The C-5 substituted 2,4-diaminoquinazoline RG3039 (compound 1), a member of a chemical series that was identified and optimized using an SMN2 promoter screen, prolongs survival and improves motor function in a mouse model of spinal muscular atrophy (SMA).

A transition metal complex compound, and the compound of the catalyst and a catalyst for large amt. pentavelent carried out in the presence of an olefin multimer manufacturing method

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Paragraph 0204-0206, (2019/08/28)

PROBLEM TO BE SOLVED: To provide a transition metal complex compound, to provide an olefin polymerizing catalyst, containing the compound, and having excellent activity, and to provide a method for producing the olefin polymer which is carried out in the presence of the catalyst.SOLUTION: There is provided the transition metal complex compound of compound 3, e.g. of chemical formula; and the olefin polymerizing catalyst including following components (A) and (B): (A) the transition metal compound; and (B) at least one compound selected from the group consisting of (B-1) an organometallic compound, (B-2) an organoaluminumoxy compound, and (B-3) a compound reactive with the transition metal compound (A), and forming an ion pair.

Asymmetric synthesis of a glucagon receptor antagonist via friedel-crafts alkylation of indole with chiral α-phenyl benzyl cation

Chung, John Y. L.,Steinhuebel, Dietrich,Krska, Shane W.,Hartner, Fred W.,Cai, Chaoxian,Rosen, Jonathan,Mancheno, Danny E.,Pei, Tao,Dimichele, Lisa,Ball, Richard G.,Chen, Cheng-Yi,Tan, Lushi,Alorati, Antony D.,Brewer, Sarah E.,Scott, Jeremy P.

, p. 1832 - 1845 (2013/01/15)

Development of a practical asymmetric synthesis of a glucagon receptor antagonist drug candidate for the treatment of type 2 diabetes is described. The antagonist consists of a 1,1,2,2-tetrasubstituted ethane core substituted with a propyl and three aryl groups including a fluoro-indole. The key steps to construct the ethane core and the two stereogenic centers involved a ketone arylation, an asymmetric hydrogenation via dynamic kinetic resolution, and an anti-selective Friedel-Crafts alkylation of a fluoro-indole with a chiral α-phenyl benzyl cation. We also developed two new efficient syntheses of the fluoro-indole, including an unusual Larock-type indole synthesis and a Sugasawa-heteroannulation route. The described convergent synthesis was used to prepare drug substance in 52% overall yield and 99% ee on multikilogram scales.

CRYSTALLINE POLYMORPHIC FORMS OF AN ANTIDIABETIC COMPOUND

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Page/Page column 18, (2010/08/04)

The present invention relates to polymorphic forms of a compound of formula A: This compound is useful as a glucagon receptor antagonist and serves as a pharmaceutically active ingredient for the treatment of type 2 diabetes and related conditions, such as hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. Hydrates, hemihydrates, anhydrates and similar polymorphic forms are included.

Synthesis of RHPS4 via an anionic ring closing cascade

Kristensen, Jesper Langgaard

, p. 2351 - 2354 (2008/09/18)

A new and convergent synthesis of the potent telomerase inhibitor RHPS4 is presented. The key step is the construction of the pentacyclic framework via an anionic ring closing cascade in which two new rings are formed.

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

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Page/Page column 54-55, (2010/11/26)

Compounds which have activity at M1 receptor and their uses in medicine Compounds of formula (I) and salts and solvates are provided: wherein R4 is fluoro, R5 is selected from hydrogen, halogen, cyano, C1-6alkyl

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