183495-92-3Relevant academic research and scientific papers
Iron-catalyzed aerobic oxidative amidation of tertiary amines with carboxylic acids
Ma, Lina,Li, Yuanming,Li, Zhiping
, p. 1310 - 1315 (2015)
An oxidative amidation of tertiary amines with carboxylic acids has been developed in the presence of FeCl3·6H2O as catalyst and oxygen as oxidant. A variety of tertiary amides were obtained in good to excellent yields from inexpensive and readily available reagents. The possible reaction pathways were investigated.
Desulfurization of Thioamides into Amides with H2O 2/ZrCl4 Reagent System
Bahrami, Kiumars,Khodaei, Mohammad Mehdi,Tirandaz, Yeganeh
experimental part, p. 369 - 371 (2009/07/04)
The hydrogen peroxide/zirconium(IV) chloride reagent system has been used as a new and efficient reagent for the deprotection/desulfurization of thioamides to amides. This system is reasonably general and can be applied to the conversion of several thioamides to the corresponding amides. The salient features of this protocol are short reaction times, good chemoselectivity, cleaner reaction profiles, and simple workup that precludes the use of toxic solvents. Georg Thieme Verlag Stuttgart.
