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(2Z)-2-[bis(2-chloroethyl)amino]but-2-enediamide, also known as 2,2'-Dichlorodiethylamine, is a synthetic nitrogen mustard derivative belonging to the class of dialkylamines. It acts as an alkylating agent, capable of adding alkyl groups to biomolecules, and has been utilized in the production of anticancer drugs for the treatment of various cancers, such as lymphoma and leukemia.

18352-46-0

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18352-46-0 Usage

Uses

Used in Pharmaceutical Industry:
(2Z)-2-[bis(2-chloroethyl)amino]but-2-enediamide is used as an active pharmaceutical ingredient for the development of anticancer drugs, specifically targeting the treatment of lymphoma and leukemia. Its alkylating properties enable it to interfere with the function and replication of cancer cells, thereby exhibiting therapeutic effects.
However, due to its high toxicity, potential health hazards, and the availability of safer alternatives, the use of (2Z)-2-[bis(2-chloroethyl)amino]but-2-enediamide in pharmaceutical applications has declined. It is essential to handle and store this chemical with extreme caution to prevent severe skin and eye irritation, respiratory issues, and long-term health risks.

Check Digit Verification of cas no

The CAS Registry Mumber 18352-46-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,5 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18352-46:
(7*1)+(6*8)+(5*3)+(4*5)+(3*2)+(2*4)+(1*6)=110
110 % 10 = 0
So 18352-46-0 is a valid CAS Registry Number.

18352-46-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-2-[bis(2-chloroethyl)amino]but-2-enediamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18352-46-0 SDS

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