18354-56-8

Basic information

• Product Name: 1-(thieno[2,3-b]pyridin-2-yl)ethanone
• CAS NO: 18354-56-8
• Molecular Formula: C₉H₇NOS
• Molecular Weight: 177.223
• Mol File: 18354-56-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318.3°C at 760 mmHg
• Flash Point: 146.3°C
• Density: 1.286g/cm³
• Vapor Pressure: 0.000365mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: 1-(thieno[2,3-b]pyridin-2-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(thieno[2,3-b]pyridin-2-yl)ethanone(18354-56-8)
• EPA Substance Registry System: 1-(thieno[2,3-b]pyridin-2-yl)ethanone(18354-56-8)

Safety Data

• Hazardous Substances Data: 18354-56-8(Hazardous Substances Data)

Usage

General Description

1-(thieno[2,3-b]pyridin-2-yl)ethanone is a chemical compound with the molecular formula C11H9NO. It is a yellow to brown solid with a strong odor and is commonly used in research and laboratory settings. 1-(thieno[2,3-b]pyridin-2-yl)ethanone is a ketone derivative containing a thieno[2,3-b]pyridine ring system, which is known for its various biological activities. It is used in the synthesis of organic compounds and is a key intermediate in the production of pharmaceuticals and agrochemicals. Additionally, it has potential applications in the field of medicinal chemistry and drug discovery due to its unique structural features. Its chemical properties and reactivity make it a valuable building block for the synthesis of novel compounds for various industries.

Upstream product

• 113975-22-7 2-fluoro-3-iodopyridine 
• 122-31-6 malondialdehyde bis(diethyl acetal) 
• 36404-88-3 2-chloro-3-carbaldehydepyridine 
• 24653-75-6 1-mercaptopropan-2-one 
• 28988-21-8 3-bromanylthieno[2,3-b]pyridine 
• 127-19-5 N,N-dimethyl acetamide 

Relevant articles and documents

Straightforward synthesis of 2-acetyl-substituted benzo[b]thiophenes

Described herein is a green one-step protocol for the preparation of substituted 2-acetylbenzo[b]thiophenes from commercially available aromatic halides. This efficient method has the advantage of using water as the reaction medium, resulting in a high yield of pure cyclized products. Two scaffold types have been prepared using this general procedure: 2-acetylbenzo[b]thiophenes and 2-acetyl-3-aminobenzo[b]thiophenes, both crystallized directly from the reaction mixture, due to their low solubility with water, and without the need for an additional purification step. Georg Thieme Verlag Stuttgart · New York.

Method for synthesizing 2-carbonyl thienopyridine compound

The invention discloses a method for synthesizing 2-carbonyl thienopyridine compound. According to the method provided by the invention, 2-halo-3-alkynol pyridine as shown in formula (I) and sulfur sources are mixed; and with the aid of a catalyst, after reacting in a solvent for a while, 2-carbonyl thienopyridine compound as shown in formula (II) is prepared after purification treatment. The sulfur sources are selected from one or more of elemental sulphur, ammonium sulfide, thiourea, sodium sulfide, and ethyl potassium xanthate, and the catalyst is selected from one of copper acetate, cuprous iodide, cuprous bromide, cuprous chloride, copper chloride, cupric acetylacetonate, palladium chloride, and copper trifluoromethanesulfonate. The technical scheme of the invention has the advantagesof less reaction steps, simple operation method, wide source of reaction substrate, low costs and easy availability of the catalyst, high product yield and the like, and the technical scheme is verysuitable for industrial mass production. The formulas are shown in the description.

DIHYDROISOXAZOLE COMPOUNDS, PARASITICIDAL USES AND FORMULATIONS THEREOF

Provided are dihydroisoxazole compounds useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier.