18354-57-9 Usage
Description
1-(Thieno[2,3-b]pyridin-5-yl)ethanone is a heterocyclic chemical compound characterized by the molecular formula C10H7NOS. It features a thieno[2,3-b]pyridine ring system fused with an ethanone functional group, which endows it with unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Research and Development:
1-(Thieno[2,3-b]pyridin-5-yl)ethanone serves as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs with diverse therapeutic profiles. Its unique structure allows for the exploration of its potential as a lead compound in medicinal chemistry.
Used in Agrochemical Research and Development:
In the agrochemical industry, 1-(Thieno[2,3-b]pyridin-5-yl)ethanone is utilized for the research and development of novel agrochemicals, such as pesticides and herbicides. Its heterocyclic nature may offer new avenues for the design of more effective and environmentally friendly agrochemicals.
Used in Organic Synthesis:
1-(Thieno[2,3-b]pyridin-5-yl)ethanone acts as an important intermediate in organic synthesis, facilitating the preparation of various organic compounds with potential applications in different industries, including materials science, pharmaceuticals, and agrochemicals.
Used in Medicinal Chemistry:
1-(Thieno[2,3-b]pyridin-5-yl)ethanone is employed as a building block in the design and synthesis of new medicinal agents, leveraging its heterocyclic structure to explore its potential therapeutic effects and mechanisms of action.
Used in Neurpharmacology:
Due to its potential biological activities, such as anticonvulsant and sedative effects, 1-(Thieno[2,3-b]pyridin-5-yl)ethanone is studied for its applications in neuropharmacology. It may contribute to the development of new treatments for neurological disorders and conditions related to the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 18354-57-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,5 and 4 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18354-57:
(7*1)+(6*8)+(5*3)+(4*5)+(3*4)+(2*5)+(1*7)=119
119 % 10 = 9
So 18354-57-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NOS/c1-6(11)8-4-7-2-3-12-9(7)10-5-8/h2-5H,1H3
18354-57-9Relevant articles and documents
Metal free coupling of heteroaryl N-tosylhydrazones and thiols: Efficient synthesis of sulfides
García-Carrillo, Mario Alfredo,Guzmán, ángel,Díaz, Eduardo
supporting information, p. 1952 - 1956 (2017/04/27)
A metal free coupling of heteroaromatic N-tosylhydrazones with thiols is presented. A convenient synthetic route to synthesize heteroaryl N-tosylhydrazones is also showed. Valuable thioethers with pyrroles, pyridines, thieno[2,3-b]pyridines, imidazo[1,2-a]pyridines, and 6H-thieno[2,3-b]pyrroles derivatives were synthesized in good yields. This coupling reaction can be carried out in a one-pot fashion and scaled up to the gram scale by using heteroaryl aldehydes, without the need to isolate the N-tosylhydrazone.
SYNTHESIS, COMPLEXATION STUDY AND REACTIVITY OF ANNELATED THIOPHENIC NADH MODELS.
Cazin, J.,Trefouel, T.,Dupas, G.,Bouguignon, J.,Queguiner, G.
, p. 1079 - 1090 (2007/10/02)
The synthesis of two carbamoyl 4,7-dihydrothienopyridines 1a and 1b is described.These derivatives are potential new NADH models.A NMR study of the complexation of magnesium ions by these compounds has been performed.The behaviour of the thieno derivative is different of that of thieno derivative: in the former the sulfur atom plays an impotant role in the complexation.The biomimetic reduction of p.nitrobenzaldehyde with 1a or 1b has been studied.The reactivity of the thiophenic annelated NADH models is very superior to that of quinoline analogous.It can be compared to the reactivity of common models such as N-benzyl 1,4-dihydronicotinamide (BNAH).Moreover 1a and 1b can be used in conditions were BNAH is much more less effective.
