183545-05-3 Usage
General Description
6-Chloro-3-(tributylstannyl)pyridine is a chemical compound consisting of a chlorine atom, a pyridine ring, and a tributylstannyl group. It is utilized in organic synthesis as a reagent for the introduction of a tributylstannyl group to other molecules. 6-Chloro-3-(tributylstannyl)pyridine is highly reactive due to the presence of the tributylstannyl substituent, which can easily undergo substitution reactions with various electrophiles. It is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in the preparation of functionalized aromatic compounds for use in materials chemistry. Safety precautions should be taken when handling this compound, as tributylstannyl groups are toxic and can have harmful effects on health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 183545-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,5,4 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 183545-05:
(8*1)+(7*8)+(6*3)+(5*5)+(4*4)+(3*5)+(2*0)+(1*5)=143
143 % 10 = 3
So 183545-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H3ClN.3C4H9.Sn/c6-5-3-1-2-4-7-5;3*1-3-4-2;/h1,3-4H;3*1,3-4H2,2H3;/rC17H30ClNSn/c1-4-7-12-20(13-8-5-2,14-9-6-3)16-10-11-17(18)19-15-16/h10-11,15H,4-9,12-14H2,1-3H3
183545-05-3Relevant articles and documents
Nickel-catalyzed cross-electrophile coupling of 2-chloropyridines with alkyl bromides
Everson, Daniel A.,Buonomo, Joseph A.,Weix, Daniel J.
supporting information, p. 233 - 238 (2014/02/14)
The synthesis of 2-alkylated pyridines by the nickel-catalyzed cross-coupling of two electrophiles, a 2-chloropyridine and an alkyl bromide, is described. Compared with our previously published conditions for aryl halides, this method uses a different, more rigid, bathophenanthroline ligand and is conducted at high concentration in N,N-dimethylformamide as solvent. The method displays promising functional group compatibility and the conditions are orthogonal to those for the Stille coupling.Georg Thieme Verlag Stuttgart.
