183545-05-3 Usage
Uses
Used in Organic Synthesis:
6-Chloro-3-(tributylstannyl)pyridine is used as a reagent for the introduction of a tributylstannyl group to other molecules, facilitating the synthesis of complex organic compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 6-Chloro-3-(tributylstannyl)pyridine is utilized as a key intermediate in the synthesis of various drugs, contributing to the development of new therapeutic agents.
Used in Agrochemical Synthesis:
6-Chloro-3-(tributylstannyl)pyridine is employed as a building block in the production of agrochemicals, aiding in the creation of effective pesticides and other agricultural products.
Used in Materials Chemistry:
6-Chloro-3-(tributylstannyl)pyridine is also used in the preparation of functionalized aromatic compounds for applications in materials chemistry, such as the development of advanced materials with specific properties.
Safety Precautions:
When handling 6-Chloro-3-(tributylstannyl)pyridine, it is crucial to take safety precautions due to the toxicity of tributylstannyl groups, which can have harmful effects on health and the environment. Proper protective equipment and disposal methods should be employed to minimize risks.
Check Digit Verification of cas no
The CAS Registry Mumber 183545-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,5,4 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 183545-05:
(8*1)+(7*8)+(6*3)+(5*5)+(4*4)+(3*5)+(2*0)+(1*5)=143
143 % 10 = 3
So 183545-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H3ClN.3C4H9.Sn/c6-5-3-1-2-4-7-5;3*1-3-4-2;/h1,3-4H;3*1,3-4H2,2H3;/rC17H30ClNSn/c1-4-7-12-20(13-8-5-2,14-9-6-3)16-10-11-17(18)19-15-16/h10-11,15H,4-9,12-14H2,1-3H3
183545-05-3Relevant academic research and scientific papers
Nickel-catalyzed cross-electrophile coupling of 2-chloropyridines with alkyl bromides
Everson, Daniel A.,Buonomo, Joseph A.,Weix, Daniel J.
supporting information, p. 233 - 238 (2014/02/14)
The synthesis of 2-alkylated pyridines by the nickel-catalyzed cross-coupling of two electrophiles, a 2-chloropyridine and an alkyl bromide, is described. Compared with our previously published conditions for aryl halides, this method uses a different, more rigid, bathophenanthroline ligand and is conducted at high concentration in N,N-dimethylformamide as solvent. The method displays promising functional group compatibility and the conditions are orthogonal to those for the Stille coupling.Georg Thieme Verlag Stuttgart.
FUSED THIAZOLE DERIVATIVES HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR
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Page/Page column 25, (2008/06/13)
The present invention relates to novel fused thiazole derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
