183547-74-2

Usage

InChI:InChI=1/C7H6F9I/c8-4(9,2-1-3-17)5(10,11)6(12,13)7(14,15)16/h1-3H2

Upstream product

• 344397-43-9 1-methanesulfonyloxy-4,4,5,5,6,6,7,7,7-nonafluoroheptane 
• 80233-96-1 3?(perfluoro?n?butyl)?2?iodo?1?propanol 
• 83310-97-8 4,4,5,5,5,6,6,7,7,7-nonafluoro-1-heptanol 

Downstream Products

• 1071967-81-1 C₁₇H₁₉F₉O₂ 

Relevant academic research and scientific papers

Preparation of (perfluoroalkyl)alkane thiols via Zemplén deacylation of fluorous (perfluoroalkyl)alkyl thioacetates

Convenient and robust synthesis of (perfluoroalkyl)alkane thiols [(CnF2n+1(CH2)mSH); m/n = 3/4,6,8,10, 4a-d; m/n = 2/6, 8; m/n = 1/1,2,3,7,8H, 12a-e] was developed starting from commercially available fluorous alcohols (1a-d, 5, 9a-e). The intermediate (perfluoroalkyl)alkyl iodides and/or sulfonates were reacted with potassium thioacetate in DMF, and the resulting thioacetates were deacetylated by a Zemplén analogue reaction. The (perfluoroalkyl)alkane thiols were obtained in good overall yields and high purity.

Liquid crystalline and charge transport properties of novel non-peripherally octasubstituted perfluoroalkylated phthalocyanines

Two new perfluoroalkylated phthalocyanine derivatives were synthesised and characterised in order to investigate the effects of the fluorophobic/fluorophilic interactions on their mesophase and electronic properties. Both compounds exhibit columnar mesomo

Fluorous dimethylthiocarbamate (FDMTC) protecting groups for alcohols

N,N-Bis(perfluoroalkyl)thiocarbamoyl chlorides (FDMTC-Cls) were synthesized as reagent for the protection of alcohols. Using the crystalline FDMTC-Cls, the FDMTC groups were introduced into the alcohol molecules in excellent yields in the presence of sodium hydride in THF at room temperature. The products were separated from the excess alcohols by solid-phase extraction with a fluorous reverse-phase silica gel column (Fluorous Solid Phase Extraction; FSPE). The FDMTC groups were readily removed by oxidation with m-chloroperbenzoic acid (m-CPBA) and subsequent hydrolysis with KHCO3.

3-methyl-chroman and -thiochroman derivatives

The present invention provides a compound having the following general formula (1): in which R1represents a hydrogen atom, etc.; R2represents a C3-C3perhalogenoalkyl group, etc.; each of R3and R4independently represents a hydrogen atom, etc.; X represents an oxygen atom or a sulfur atom; m represents an integer of 2 to 14; and n represents an integer of 0 to 8; or enantiomers of the compound, or hydrates or pharmaceutically acceptable salts of the compound or its enantiomers. The compound of general formula (1) is advantageous in pharmaceutical use because of its anti-estrogenic activity.