18357-38-5

Usage

Uses

Used in Organic Synthesis:
3,5-diphenyl-4H-pyran-4-one is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of diverse chemical entities through reactions such as electrophilic substitution, nucleophilic addition, and rearrangement reactions.
Used in Material Science:
3,5-diphenyl-4H-pyran-4-one is utilized in the development of new materials with specific properties. Its incorporation into polymers, coatings, and other materials can lead to improved characteristics such as enhanced stability, solubility, and optical properties.
Used in Biological Activities:
3,5-diphenyl-4H-pyran-4-one has been investigated for its potential biological activities, including its effects on cellular processes and its interactions with biological targets. 3,5-diphenyl-4H-pyran-4-one may have applications in the development of pharmaceuticals, agrochemicals, and other bioactive compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,5-diphenyl-4H-pyran-4-one is used as a starting material or a building block for the synthesis of drug candidates. Its unique chemical properties and potential biological activities make it a valuable component in the development of new therapeutic agents.
Used in Agrochemical Industry:
3,5-diphenyl-4H-pyran-4-one is employed in the agrochemical industry as a precursor for the synthesis of pesticides, herbicides, and other crop protection agents. Its chemical versatility allows for the creation of compounds with targeted biological activities to improve crop yields and protect against pests.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 3,5-diphenyl-4H-pyran-4-one is used as a colorant or a component in the synthesis of dyes and pigments. Its yellow color and stability make it suitable for various applications, including textiles, plastics, and printing inks.

Upstream product

• 75335-25-0 meso-2,4-Diphenyl-1,1,5,5-tetramethoxy-3-pentanon 
• 75335-25-0 (+/-)-2,4-Diphenyl-1,1,5,5-tetramethoxy-3-pentanon 
• 73178-51-5 1,5-bis(dimethylamino)-2,4-diphenylpenta-1,4-dien-3-one 
• 68-12-2 N,N-dimethyl-formamide 
• 102-04-5 1,3-Diphenylpropanone 
• 745836-46-8 4-dimethylamino-1,3-diphenyl-but-3-en-2-one 

Downstream Products

• 80837-89-4 3,5-Diphenyl-[1,2']bipyridinyl-4-one 
• 80837-85-0 4-(4-Oxo-3,5-diphenyl-4H-pyridin-1-yl)-benzoic acid 
• 80837-83-8 2-(4-Oxo-3,5-diphenyl-4H-pyridin-1-yl)-benzoic acid 
• 80837-81-6 1-(3-Chloro-phenyl)-3,5-diphenyl-1H-pyridin-4-one 
• 80837-87-2 1-(2-Hydroxy-phenyl)-3,5-diphenyl-1H-pyridin-4-one 
• 80837-79-2 1-(2-Chloro-phenyl)-3,5-diphenyl-1H-pyridin-4-one 
• 80837-88-3 1-(3-Hydroxy-phenyl)-3,5-diphenyl-1H-pyridin-4-one 
• 80837-78-1 3,5-Diphenyl-1-o-tolyl-1H-pyridin-4-one 

Relevant academic research and scientific papers

Enaminones as building blocks in heterocyclic synthesis: New syntheses of nicotinic acid and thienopyridine derivatives

Reacting 1,3-diphenyl-propan-2-one with equimolecular amount of dimethylformamide dimethylacetal afforded the enaminone 4. This when reacted with another equimolecular amount of dimethylformamide dimethylacetal afforded the dienaminone 5. Compound 4 condenses with cyanothioacetamide and with cyanoacetamide to yield 2-thioxo- and 2-oxo-pyridine-3-carbonitrile derivatives 6a,b respectively. Compound 6a reacted with (x-chloroacetone 8 to yield the thieno[2,3-b]pyridine derivative 10 that cyclized further into 4,7,8-trisubstituted pyrido[2′,3′:2,3] thieno[4,5-d]pyrimidine 12. Compound 4 also afforded 2,5,6-trisubstituted nicotinic acid ethyl ester 13 by reaction with ethyl acetoacetate in acetic acid in the presence of ammonium acetate. The dienaminone 5 reacted with acetic acid, ammonium acetate/acetic acid, phenylhydrazine and 5-amino-3-methylpyrazole yielding 3,5-diphenyl-pyran- 4-one 15a, 3,5-diphenyl-1H-pyridin-4-one 15b and 1,3,5-trisubstituted pyridin-4-ones 16a-b.

Vilsmeier-Haack reactions of carbonyl compounds: Synthesis of substituted pyrones and pyridines

Vilsmeier-Haack reaction of substituted phenylacetones leads to the formation of conjugated iminium salts which on aqueous basic work up afford 3-formyl-4-pyrones and on ammonium acetate-induced cyclization afford 5-aryl-4-chloronicotinaldehydes in good y

Oxidative Rearrangement of α-Benzylideneketones with Thallium(III) Nitrate in Methanol

Sterically unhindered arylidene- and diarylideneacetones 1 or 2 having electron releasing aryl groups yielded with thallium(III) nitrate in methanol β-ketoacetals 3, 4 and 5, respectively.Electronegatively substituted 1f and sterically hindered 1g and 1h gave the 4-arylcrotonic esters 7 and by-products, while 1,3-dibenzylidenacetone (2a) yielded besides the expected products also the branched acetal esters 13a and 13b.Formation of the anomalous products 7 and 13 can be rationalized assuming a common cyclopropanone type intermediate.