Aminooxy-PEG3-t-butyl ester is an aminooxy-containing PEG molecule that features a hydrophilic PEG spacer, which enhances solubility in aqueous media. The reactive aminooxy group can form an oxime bond with an aldehyde, and with the use of a reductant, it can create a hydroxylamine linkage. The t-butyl ester group is convertible to a free acid under acidic conditions. Due to their high reactivity and sensitivity, aminooxy compounds are not suitable for long-term storage and should be used immediately, preferably within one week.
1835759-72-2
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Basic information
- Product Name: Aminooxy-PEG3-t-butyl ester
- Synonyms: Aminooxy-PEG3-t-butyl ester
- CAS NO:1835759-72-2
- Molecular Formula: C13H27NO6
- Molecular Weight: 293.35658
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1835759-72-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Aminooxy-PEG3-t-butyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: Aminooxy-PEG3-t-butyl ester(1835759-72-2)
- EPA Substance Registry System: Aminooxy-PEG3-t-butyl ester(1835759-72-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1835759-72-2(Hazardous Substances Data)
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1835759-72-2 Usage
Uses
Used in Bioconjugation Applications:Aminooxy-PEG3-t-butyl ester is used as a bioconjugation agent for the formation of stable oxime and hydroxylamine linkages with aldehyde-containing biomolecules. Its hydrophilic PEG spacer improves the solubility and stability of the conjugates in aqueous environments, making it suitable for various biological and pharmaceutical applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Aminooxy-PEG3-t-butyl ester is utilized as a component in drug delivery systems. Its ability to form stable linkages with drug molecules and the hydrophilic nature of the PEG spacer contribute to the controlled release and targeted delivery of therapeutic agents, enhancing their bioavailability and efficacy.
Used in Chemical Synthesis:
Aminooxy-PEG3-t-butyl ester is employed as a reactive intermediate in the synthesis of various chemical compounds. Its reactivity with aldehydes and the subsequent formation of oxime or hydroxylamine bonds make it a valuable building block for the development of new materials and molecules with specific properties and functions.
Used in Materials Science:
In the field of materials science, Aminooxy-PEG3-t-butyl ester is used as a modifying agent to introduce functional groups and improve the properties of various materials. The PEG spacer and reactive aminooxy group allow for the creation of novel materials with enhanced solubility, stability, and reactivity, which can be applied in diverse areas such as sensors, coatings, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 1835759-72-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,3,5,7,5 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1835759-72:
(9*1)+(8*8)+(7*3)+(6*5)+(5*7)+(4*5)+(3*9)+(2*7)+(1*2)=222
222 % 10 = 2
So 1835759-72-2 is a valid CAS Registry Number.
1835759-72-2Upstream product
1835759-72-2Downstream Products
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Aminooxy-PEG3-t-butyl ester
