183583-85-9Relevant academic research and scientific papers
Pyrazolidine derivative radical scavenger brain-infarction depressant and brain-edema depressant
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, (2008/06/13)
A pyrazolidine derivative or a salt thereof in accordance with the present invention is expressed by the following formula 1: STR1 wherein A represents a group expressed by --CH2 --, --CO--, --CS--, --CH2 CO--, or --CH=CH--CO--; B represents a group expressed by --O-- or --NH--; n is an integer of 1 or 2; R represents an alkenyl group; and R1 and R2 represent a lower alkyl or benzyl group. The pyrazolidine derivative above mentioned, as a radical scavenger, has antioxidant effect and lipid peroxidation inhibitory activity so as to be available for inhibiting brain infarction or brain edema.
