183583-95-1Relevant academic research and scientific papers
Pyridine derivative, anti-ulcer drug, and antibacterial drug
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, (2008/06/13)
A pyridine derivative or a salt thereof expressed by the following formula 1: STR1 wherein W represents a group expressed by the following formula 2 or formula 3; STR2 wherein R1 represents an alkenyloxy group; n represents 1 or 2; Ra represents a lower alkyl group; and Rb represents a halogen atom; and wherein each of R2 and R3 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, or halogenated alkyl group; Y represents a group expressed by --S--, --NH-- or --CONH--; m represents an integer of 0 to 2; and p represents 0 or 1. The pyridine derivative has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulcers.
Pyrazolidine derivative radical scavenger brain-infarction depressant and brain-edema depressant
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, (2008/06/13)
A pyrazolidine derivative or a salt thereof in accordance with the present invention is expressed by the following formula 1: STR1 wherein A represents a group expressed by --CH2 --, --CO--, --CS--, --CH2 CO--, or --CH=CH--CO--; B represents a group expressed by --O-- or --NH--; n is an integer of 1 or 2; R represents an alkenyl group; and R1 and R2 represent a lower alkyl or benzyl group. The pyrazolidine derivative above mentioned, as a radical scavenger, has antioxidant effect and lipid peroxidation inhibitory activity so as to be available for inhibiting brain infarction or brain edema.
