183609-64-5

Upstream product

• 183609-61-2 ((4S,5S)-2,2-dimethyl-5-(((triisopropylsilyl)oxy)methyl)-1,3-dioxolan-4-yl)methanol 
• 50622-09-8 2,3-O-isopropylidene-L-threitol 
• 13154-24-0 triisopropylsilyl chloride 
• 54314-85-1 (3-benzyloxypropyl)triphenylphosphonium bromide 

Downstream Products

• 183609-99-6 (R)-1-((S)-2-{(S)-2-[(S)-2-Benzyloxycarbonylamino-7-((4S,5S)-2,2-dimethyl-5-triisopropylsilanyloxymethyl-[1,3]dioxolan-4-yl)-heptanoylamino]-3-phenyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 183610-00-6 Toluene-4-sulfonic acid (4S,5S)-5-[5-((5S,8S,11S,13aR)-5,8-dibenzyl-4,7,10,13-tetraoxo-tetradecahydro-3a,6,9,12-tetraaza-cyclopentacyclododecen-11-yl)-pentyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 183609-79-2 (R)-1-((S)-2-{(S)-2-[(S)-2-Amino-7-((4S,5S)-2,2-dimethyl-5-triisopropylsilanyloxymethyl-[1,3]dioxolan-4-yl)-heptanoylamino]-3-phenyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 
• 183610-01-7 Toluene-4-sulfonic acid (2S,3S)-8-((5S,8S,11S,13aR)-5,8-dibenzyl-4,7,10,13-tetraoxo-tetradecahydro-3a,6,9,12-tetraaza-cyclopentacyclododecen-11-yl)-2,3-dihydroxy-octyl ester 
• 197631-11-1 C₃₆H₄₇⁽³⁾HN₄O₇ 
• 183609-81-6 (5S,8S,11S,13aR)-5,8-Dibenzyl-11-[5-((4S,5S)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pentyl]-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone 
• 183609-73-6 (S)-2-Benzyloxycarbonylamino-7-((4S,5S)-2,2-dimethyl-5-triisopropylsilanyloxymethyl-[1,3]dioxolan-4-yl)-heptanoic acid 

Relevant academic research and scientific papers

Synthesis of natural and modified trapoxins, useful reagents for exploring histone deacetylase function

Trapoxin, a cyclotetrapeptide isolated from the fungus Helicoma ambiens, profoundly affects mammalian cell growth and morphology. In this paper, we describe syntheses of trapoxin, [3H]trapoxin, and K-trap, a trapoxin-based affinity reagent. The