183610-81-3

Upstream product

• 16666-79-8 hexylidenetriphenylphosphoran 
• 205808-77-1 2-Benzenesulfonyl-2-{(1S,2S)-2-[(R)-5-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxy)-pentyl]-cyclopropyl}-1-[(4R,5S)-2,2-dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolan-4-yl]-ethanol 
• 183610-96-0 Biphenyl-4-carboxylic acid (2S,3R)-3-(4-hydroxy-butyl)-oxiranylmethyl ester 
• 183962-07-4 (1S,2S)-2-[(R)-5-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxy)-pentyl]-cyclopropanecarbaldehyde 
• 183610-78-8 (1R,2S)-2-[(R)-5-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxy)-pentyl]-cyclopropanecarbaldehyde 
• 183610-79-9 (1S,2S,1'R)-1-(5'-tert-butyldimethylsiloxy-1'-tert-butyldiphenylsiloxypentyl)-2-phenylsulfonylmethylcyclopropane 
• 183610-89-1 C₃₇H₅₄O₂SSi₂ 
• 183610-88-0 {(1S,2S)-2-[(R)-5-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxy)-pentyl]-cyclopropyl}-methanol 
• 205808-73-7 (R)-1-((R)-2-Benzenesulfonyl-2-vinyl-cyclopropyl)-5-(tert-butyl-dimethyl-silanyloxy)-pentan-1-ol 
• 183610-97-1 Biphenyl-4-carboxylic acid (2S,3R)-3-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-oxiranylmethyl ester 
• 183610-76-6 Methanesulfonic acid (2S,3R)-3-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-oxiranylmethyl ester 
• 183814-78-0 {(2S,3R)-3-[4-(tert-Butyl-dimethyl-silanyloxy)-butyl]-oxiranyl}-methanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 121352-74-7 (2Z)-7-[(tert-butyldimethylsilyl)oxy]hept-2-en-1-ol 

Downstream Products

• 205808-92-0 (R)-5-(tert-Butyl-diphenyl-silanyloxy)-5-((1S,2R)-2-{(E)-2-[(4R,5S)-2,2-dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolan-4-yl]-vinyl}-cyclopropyl)-pentan-1-ol 
• 183610-92-6 (R)-5-(tert-Butyl-diphenyl-silanyloxy)-5-[(1S,2R)-2-((1E,6Z)-(3R,4S)-3,4-dihydroxy-dodeca-1,6-dienyl)-cyclopropyl]-pentanoic acid methyl ester 
• 205808-82-8 (R)-5-(tert-Butyl-diphenyl-silanyloxy)-5-((1S,2R)-2-{(E)-2-[(4R,5S)-2,2-dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolan-4-yl]-vinyl}-cyclopropyl)-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of constanolactone E, a marine eicosanoid from the alga constantinea simplex; absolute structure of constanolactone E

Synthesis of marine eicosanoid constanolactone E was achieved through the one-pot formation of chiral cyclopropane derivative (6) using the anion of allyl phenyl sulfone and chiral epoxy mesylate (5). The absolute structure of constanolactone E was determined as 1 by the present synthesis.

Synthesis of constanolactone E

Synthesis of marine eicosanoid constanolactone E was achieved through the one-pot formation of chiral cyclopropane derivative 4 using the anion of allyl phenyl sulfone and chiral epoxymesylate 3.