18362-51-1

Basic information

• Product Name: 1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE
• Synonyms: 1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE;1,3-bis(4-methoxyphenyl)propane-1,3-dione;1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDION;44DIMETHOXYDIBENZOYLMETHANE;1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE 98+%;1,3-Bis(p-methoxyphenyl)-1,3-propanedione;Parsol DAM;1,3-Propanedione,1,3-bis(4-Methoxyphenyl)-
• CAS NO: 18362-51-1
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.31
• EINECS: 242-233-2
• Product Categories: Environmentally-friendly Oxidation;Ligands (Environmentally-friendly Oxidation);Synthetic Organic Chemistry;C15 to C38;Carbonyl Compounds;Ketones
• Mol File: 18362-51-1.mol
• Article Data: 50

Chemical Properties

• Melting Point: 108-115 °C(lit.)
• Boiling Point: 463.7 °C at 760 mmHg
• Flash Point: 206.4 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 3.56E-05mmHg at 25°C
• Refractive Index: 1.651
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 9.92±0.13(Predicted)
• CAS DataBase Reference: 1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE(18362-51-1)
• EPA Substance Registry System: 1,3-BIS(4-METHOXYPHENYL)-1,3-PROPANEDIONE(18362-51-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 18362-51-1(Hazardous Substances Data)

Usage

Uses

1,3-Bis(4-methoxyphenyl)-1,3-propanedione (Hpmdbm) may be used:As a reactant in the preparation of 1,3-bis(4-hydroxyphenyl)-1,3-propanedione.As a starting material in the synthesis of propylpyrazole triol (PPT).As a ligand in the synthesis of [NaFe6(OCH3)12(pmdbm)6]ClO4, an iron(III)-oxo cluster.

General Description

1,3-Bis(4-methoxyphenyl)-1,3-propanedione is a diketone. It is formed as an intermediate during the synthesis of bisphenols.

InChI:InChI=1/C11H12N2O/c14-11-9-5-2-1-4-8(9)10-12-6-3-7-13(10)11/h1-2,4-5,10,12H,3,6-7H2

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 123-54-6 acetylacetone 
• 710949-40-9 2-chloro-1,3-bis(4′-methoxy-phenyl)-1,3-propanedione 
• 54519-18-5 4,4'-dimethoxydibenzoylmethane 
• 65418-71-5 1,3-bis-(4-methoxyphenyl)-2-ethynyl-1-one 
• 32766-61-3 4-methoxyphenylglyoxylate methyl ester 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 874-90-8 4-methoxybenzonitrile 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-09-4 4-methoxybenzoic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 1107549-15-4 cis-1,2-bis(trimethylsiloxy)-1,2-bis(4-anisyl)cyclopropane 
• 7464-46-2 p-nitrophenyl p-methoxybenzoate 
• 141-82-2 malonic acid 

Downstream Products

• 88642-51-7 <3-Oxo-1,3-bisprop-1-enyl>diphenyl-phosphat 
• 95581-17-2 2,2-Dimethyl-1,3-bis(4'-methoxyphenyl)-1,3-propanedione 
• 33074-17-8 2,2-dibromo-1,3-bis(4-methoxyphenyl)propane-1,3-dione 
• 33074-13-4 2-diazo-1,3-bis(4-methoxyphenyl)propane-1,3-dione 
• 89-41-8 4-methoxy-3-nitrobenzoic acid 
• 100-09-4 4-methoxybenzoic acid 
• 33099-85-3 (Z)-2-Hydroxy-1,4-bis-(4-methoxy-phenyl)-3-phenyl-but-2-ene-1,4-dione 
• 33099-48-8 (Z)-2-Methoxy-1,4-bis-(4-methoxy-phenyl)-3-phenyl-but-2-ene-1,4-dione 
• 33099-82-0 1,4-bis-(4-methoxy-phenyl)-3-pyridin-3-yl-butane-1,2,4-trione 
• 33074-03-2 C,C'-bis-(4-methoxy-phenyl)-C,C'-(3-pyridin-3-yl-oxirane-2,2-diyl)-bis-methanone 
• 99236-19-8 1-(4-methoxyphenyl)-2-(p-tolylthio)ethan-1-one 
• 22439-73-2 4,4'-(isoxazole-3,5-diyl)diphenol 
• 215232-69-2 κ(2)-O,O-1,3-bis(4-methoxyphenyl)propane-1,3-diolonatodimethylgallium 
• 93122-32-8 C₅H₅FeC₅H₄CH₂CH(COC₆H₄OCH₃)2 

Relevant articles and documents

PPh3-catalyzed β-selective addition of α-fluoro β-dicarbonyl compounds to allenoates

A highly selective phosphine-catalyzed β-addition of α-fluoro β-dicarbonyl compounds to allenoates has been developed. Both α-fluoro β-diketones and α-fluoro β-keto esters prove to be competent fluorocarbon nucleophiles, giving a series of the β-addition products bearing a fluorinated quaternary carbon center in good to excellent yields and with excellent regioselectivities. A plausible reaction pathway is presented.

I2-Promoted [3+2] Cyclization of 1,3-Diketones with Potassium Thiocyanate: a Route to Thiazol-2(3H)-One Derivatives

An I2-promoted strategy has been developed for the synthesis of thiazol-2(3H)-one derivatives from 1,3-diketones with potassium thiocyanate. This [3+2] cyclization reaction involves C?S and C?N bond formation and exhibits good functional group tolerance. A series of thiazol-2(3H)-one derivatives are obtained in moderate to good yields. (Figure presented.).

Direct synthesis of 2,3,5-trisubstituted pyrroles: via copper-mediated one-pot multicomponent reaction

We have developed a copper-mediated one-pot synthesis of 2,3,5-trisubstituted pyrroles from 1,3-dicarbonyl compounds and acrylates using ammonium acetate as a nitrogen source. The reaction achieves C-C and C-N bond formation and provides an efficient approach to access highly functionalized pyrroles without further raw material preparation. This method is operationally simple, compatible with a wide range of functional groups, and provides the target products in moderate to good yields. This journal is