183667-16-5Relevant academic research and scientific papers
Solid-support synthesis of di- and tetramannosylated tetrathymidylic acid
Wijsman,Filippov,Valentijn,Van Der Marel,Van Boom
, p. 397 - 401 (2007/10/03)
The easy accessible building units 5-O-(2,3,4,6-tetra-O-benzoyI-α-D-mannopyranosyl)penyl 2-cyanoethyl N,N-diisopropylphosphoramidite (9) and 2,2-bis(4,4′-dimethoxytrityloxymethyl)propyl 2-cyanoethyl N,N-diisopropylphosphoramidite (12) were used for the sequential elongation of immobilized tetrametric thymidylic acid according to a DNA synthesis protocol. Ammonolysis of the individual immobilized adducts led to the isolation of the target compounds 1 and 2.
