183670-12-4Relevant articles and documents
Design, synthesis and antibacterial evaluation of some new 2-phenyl-quinoline-4-carboxylic acid derivatives
Wang, Xiaoqin,Xie, Xiaoyang,Cai, Yuanhong,Yang, Xiaolan,Li, Jiayu,Li, Yinghan,Chen, Wenna,He, Minghua
, (2016)
A series of new 2-phenyl-quinoline-4-carboxylic acid derivatives was synthesized starting from aniline, 2-nitrobenzaldehyde, pyruvic acid followed by Doebner reaction, amidation, reduction, acylation and amination. All of the newly-synthesized compounds w
STAT3 INHIBITOR CONTAINING QUINOLINECARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT
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Page/Page column 62, (2011/06/24)
The present invention provides a STAT3 inhibitor containing as an active ingredient, a quinolinecarboxamide derivative represented by the formula (I) (in the formula, W represents a bond or an alkylene chain; X represents O, S, or NR34; and Rs
Microwave-assisted Doebner synthesis of 2-phenylquinoline-4-carboxylic acids and their antiparasitic activities
Muscia, Gisela C.,Carnevale, Juan P.,Bollini, Mariela,Asis, Silvia E.
, p. 611 - 614 (2008/09/19)
(Chemical Equation Presented) A series of twelve substituted 2-phenylquinoline-4-carboxylic acids analogous to antimalarial and antileishmanial natural products was developed via the Doebner reaction employing microwave irradiation (MW). The products were obtained in moderate yields in 0.5-3 minutes and nine of them were evaluated in vitro against the parasites responsible for malaria, leishmaniasis and trypanosomiasis diseases (WHO, Switzerland). Four compounds exhibited activity against Trypanosoma cruzi and another two resulted active against Plasmodium falciparum and Leishmania infantum, respectively.
Separation of 2(3),9(10),16(17),23(24)-tetrasubstituted phthalocyanines with newly developed HPLC phases
Sommerauer, Michael,Rager, Christine,Hanack, Michael
, p. 10085 - 10093 (2007/10/03)
The synthesis of 2(3),9(10),16(17),23(24)-tetrasubstituted phthalocyanines from 1,2-dicyano-4-alkoxybenzenes or the corresponding isoindolines is reported. In each case, four isomers with D(2h), C(4h), C(2v), and C(s) symmetry are obtained in the statisti