183674-82-0

Basic information

• Product Name: Propanamide, N-(2-mercaptophenyl)-2,2-dimethyl-
• CAS NO: 183674-82-0
• Molecular Formula: C11H15NOS
• Molecular Weight: 209.312
• Mol File: 183674-82-0.mol

Chemical Properties

• CAS DataBase Reference: Propanamide, N-(2-mercaptophenyl)-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-(2-mercaptophenyl)-2,2-dimethyl-(183674-82-0)
• EPA Substance Registry System: Propanamide, N-(2-mercaptophenyl)-2,2-dimethyl-(183674-82-0)

Safety Data

• Hazardous Substances Data: 183674-82-0(Hazardous Substances Data)

Upstream product

• 117137-42-5 2,2'-dithiobis-(N-phenyl-2,2-dimethylpropanamide) 

Downstream Products

• 1188393-08-9 S-(2-(pivaloylamino)phenyl) (E)-3-(4-(tert-butyldimethylsilyloxy)phenyl)prop-2-enethioate 
• 183674-79-5 [Fe(III)(octaethylporphyrinato)(S-2-t-BuCONHC₆H₄)] 

Relevant articles and documents

Color regulation and stabilization of chromophore by Cys69 in photoactive yellow protein active center

Model compounds of PYP chromophore were synthesized and characterized to investigate the role of the Cys69 residue in the active center, which has the intramolecular NH...OC hydrogen bond to the conjugated carbonyl oxygen and thioester linkage of the chro

CETP activity inhibitors

The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl group; a straight chain or branched alkenyl group; a lower haloalkyl group; a substituted or unsubstituted cycloalkyl group; a substituted or unsubstituted cycloalkenyl group; a substituted or unsubstituted cycloalkylalkyl group; a substituted or unsubstituted aryl group, or a substituted or unsubstituted heterocyclic group, X1, X2, X3, and X4may be the same or different and each represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower haloalkyl group; a lower alkoxy group; a cyano group; a nitro group; an acyl group; or an aryl group, Y represents —CO— or —SO2—, and Z represents a hydrogen atom or a mercapto-protecting group, or a prodrug compound, a pharmaceutically acceptable salt, or hydrate or solvate thereof. The compounds represented by the formula (I) can increase HDL and at the same time decrease LDL through selective inhibition of CETP activity and, therefore, is expected to be useful as a new type of a preventive or therapeutic agent for atherosclerosis or hyperlipidemia.