18368-71-3 Usage
Uses
Used in Pharmaceutical Industry:
4-Methyl-2-nitropyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Methyl-2-nitropyridine serves as an essential intermediate for the production of pesticides and other crop protection agents. Its incorporation into these products helps enhance their effectiveness in controlling pests and diseases.
Used in Dye and Pigment Industry:
4-Methyl-2-nitropyridine is utilized as a building block in the creation of dyes and pigments, contributing to their color intensity and stability. Its presence in these products ensures their long-lasting and vibrant appearance.
Used in Specialty Chemicals Production:
4-Methyl-2-nitropyridine is also employed in the production of specialty chemicals, which are used in a wide range of applications, such as coatings, adhesives, and plastics. Its versatility and reactivity make it a valuable component in the synthesis of these high-performance materials.
Check Digit Verification of cas no
The CAS Registry Mumber 18368-71-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,6 and 8 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18368-71:
(7*1)+(6*8)+(5*3)+(4*6)+(3*8)+(2*7)+(1*1)=133
133 % 10 = 3
So 18368-71-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H20O4Si2/c1-14(2,3)12-8(10)7-9(11)13-15(4,5)6/h7H2,1-6H3
18368-71-3Relevant academic research and scientific papers
Substitution of the nitro group with Grignard reagents: Facile arylation and alkenylation of pyridine N-oxides
Zhang, Fang,Zhang, Song,Duan, Xin-Fang
supporting information, p. 5618 - 5620 (2013/01/15)
The unprecedented substitution of a nitro group with aryl or alkenyl groups of Grignard reagents affords 2-aryl or alkenylpyridine N-oxides in modest to high yields with high chemoselectivity. This protocol allows a simple and clean synthesis of various 2
Zirconium-catalysed Oxidation of Primary Aromatic Amines to Nitro Compounds Using tert-Butylhydroperoxide
Krohn, Karsten,Kuepke, Jochen,Rieger, Hagen
, p. 335 - 339 (2007/10/03)
A broad range of primary aromatic amines (1a-x) with electron donating and accepting substituents are oxidized in good to excellent yields to the nitro compounds 3a-x using tert-butylhydroperoxide as the oxidant and Zr(OtBu)4 as the catalyst. The corresponding nitroso compounds 2m,-2n, 2s and 2u can be isolated in the conversion of electron-rich anilines 1m, 1n, 1s and 1u. The aminopyridines 5a-d are also converted to the corresponding nitropyridines 6a-d, but in lower yields (41-47%).
