183721-15-5

Basic information

• Product Name: 9-CHLORO-2-(2-FURANYL)-5-[(PHENYLACETY)AMINO][1,2,4]-TRIAZOLO[1,5-C] QUINAZOLINE
• Synonyms: 9-CHLORO-2-(2-FURANYL)-5-[(PHENYLACETY)AMINO][1,2,4]-TRIAZOLO[1,5-C] QUINAZOLINE;N-[9-CHLORO-2-(2-FURANYL)[1,2,4]-TRIAZOLO[1,5-C]QUINAZOLIN-5-YL]BENZENE ACETAMIDE;MRS 1220;9-chloro-2-(2-furanyl)-5-((phenylacetyl)amino)-[1,2,4]triazolo[1,5-c]quinazoline;9-CHLORO-2-(2-FURANYL)-5-((PHENYLACETYL)AMINO)-[1,2,4]TRIAZOLO[1,5-C]QUINA
• CAS NO: 183721-15-5
• Molecular Formula: C21H14ClN5O2
• Molecular Weight: 403.82
• Mol File: 183721-15-5.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: white/solid
• Density: 1.49g/cm³
• Refractive Index: 1.744
• Storage Temp.: Store at RT
• Solubility: DMSO: 2 mg/mL
• CAS DataBase Reference: 9-CHLORO-2-(2-FURANYL)-5-[(PHENYLACETY)AMINO][1,2,4]-TRIAZOLO[1,5-C] QUINAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 9-CHLORO-2-(2-FURANYL)-5-[(PHENYLACETY)AMINO][1,2,4]-TRIAZOLO[1,5-C] QUINAZOLINE(183721-15-5)
• EPA Substance Registry System: 9-CHLORO-2-(2-FURANYL)-5-[(PHENYLACETY)AMINO][1,2,4]-TRIAZOLO[1,5-C] QUINAZOLINE(183721-15-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 183721-15-5(Hazardous Substances Data)

Usage

Uses

MRS 1220 is a highly potent and selective human Adenosine A3-R antagonist.

Biological Activity

A potent and highly selective antagonist at the human A 3 adenosine receptor (K i values are 0.65, 305, and 52 nM at hA 3 , rA 1 and rA 2A respectively. Displays an IC 50 value > 1 μ M for inhibition of binding to rat A 3 receptors).

InChI:InChI=1/C21H14ClN5O2/c22-14-8-9-16-15(12-14)20-25-19(17-7-4-10-29-17)26-27(20)21(23-16)24-18(28)11-13-5-2-1-3-6-13/h1-10,12H,11H2,(H,23,24,28)