183739-72-2

Upstream product

• 3189-43-3 tetracyanoethylene oxide 
• 90854-70-9 3-nitro-dithiobenzoic acid methyl ester 

Downstream Products

• 183738-69-4 4-(3-chloro-phenylamino)-3-(3-nitro-phenyl)-1H-pyrazolo[3,4-d]pyrimidine 
• 183739-73-3 5-amino-3-(3-nitrophenyl)-1H-pyrazole-4-carbonitrile 

Relevant academic research and scientific papers

Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(Phenylamino)pyrazolo[3,4-d]pyrimidines

In the course of the random screening of a pool of CIBA chemicals, the two pyrazolopyrimidines 1 and 2 have been identified as fairly potent inhibitors of the EGF-R tyrosine kinase. Using a pharmacophore model for ATP- competitive inhibitors interacting w