18378-24-0Relevant academic research and scientific papers
ASPARAGINE ENDOPEPTIDASE (AEP) INHIBITORS, COMPOSITIONS, AND USES RELATED THERETO
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Page/Page column 4; 54; 62, (2020/12/11)
This disclosure relates to asparagine endopeptidase inhibitors and compositions and uses related thereto. In certain embodiments, the asparagine endopeptidase inhibitors are useful for improving memory, treating or preventing cancer, neurodegenerative diseases, and cognitive disorders. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising an asparagine endopeptidase inhibitor and a pharmaceutically acceptable excipient.
METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS
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Page/Page column 79, (2009/04/25)
Methods for overcoming multiple herbicide resistance (MHR) in plants using inhibitors of GST suppression of Formula (I), novel chemical inhibitors of Formula (Ia), compositions comprising compounds of Formula (I), and uses and methods relating thereto.
Unusual reaction of 4-nitrobenzofurazan with amines
Levinson, Feliks S.,Varganov, Roman V.,Zakiev, Marsel M.,Shakirova, Ilmira M.,Sheremetev, Aleksei B.,Dmitriev, Dmitry E.,Krivolapov, Dmitry B.,Litvinov, Igor A.,Sharafutdinova, Dilyara R.,Efremov, Yurii Ya.
body text, p. 329 - 331 (2009/05/27)
The treatment of 4-nitrobenzofurazan with secondary amines resulted in the formation of 4-amino-5,7-bis(dialkylamino)-benzofurazans, as established by X-ray diffraction analyses; this is the first example of SNH reaction with synchro
Derivatization of Amines with 4-Substituted 7-Nitrobenzofurazans
Heberer, H.,Kersting, H.,Matschiner, H.
, p. 487 - 504 (2007/10/02)
Electrophilic derivatives of 4-nitro-benzofurazan with different reactivities were used to synthesize 28 new mono- and disubstituted 4-amino-7-nitrobenzofurazans 2b, 2d, 2f-2i, 2l, 2m-2n, 3b-3f, 3h-3j, 4c-4d, 4f-4k, 4m, 4o-4p.A reaction mechanism is proposed on the basis of the differences of the reactivities and a preliminary kinetic examination.The acid character of the N-H-function in monosubstituted compounds is demonstrated by means of spectroscopical investigation of pKa-values.Data from i.r., u.v./vis, and fluorescence studies are offered.
